Publications

Sidney Altman

2023

An Outbreak Investigation of Salmonella Typhimurium Illnesses in the United States Linked to Packaged Leafy Greens Produced at a Controlled Environment Agriculture Indoor Hydroponic Operation - 2021.McClure M, Whitney B, Gardenhire I, Crosby A, Wellman A, Patel K, McCormic ZD, Gieraltowski L, Gollarza L, Low MSF, Adams J, Pightling A, Bell RL, Nolte K, Tijerina M, Frost JT, Beix JA, Boegler KA, Dow J, Altman S, Wise ME, Bazaco MC, Viazis S. J Food Prot. 2023 May; 2023 Mar 31. PMID: 37003534.
Patterns of dreissenid mussel invasions in western US lakes within an integrated gravity model framework.Carrillo CC, Charbonneau BR, Altman S, Keele JA, Pucherelli SF, Passamaneck YJ, Murphy AC, Swannack TM. J Environ Manage. 2023 Apr 15; 2023 Feb 1. PMID: 36736086.
Examination of aminophenol-containing compounds designed as antiproliferative agents and potential atypical retinoids.Chingle RM, Imai M, Altman S, Saito D, Takahashi N, Burke TR. Bioorg Med Chem. 2023 Mar 15; 2023 Feb 24. PMID: 36913882.
Vaccine hesitancy in prenatal women and mothers of newborns: Results of an interventional study.Hallas D, Altman S, Mandel E, Fletcher J. Nurse Pract. 2023 Mar 1. PMID: 36811511.

2022

Switchable targeting of solid tumors by BsCAR T cells.Stepanov AV, Kalinin RS, Shipunova VO, Zhang D, Xie J, Rubtsov YP, Ukrainskaya VM, Schulga A, Konovalova EV, Volkov DV, Yaroshevich IA, Moysenovich AM, Belogurov AA Jr, Zhang H, Telegin GB, Chernov AS, Maschan MA, Terekhov SS, Wu P, Deyev SM, Lerner RA, Gabibov AG, Altman S. Proc Natl Acad Sci U S A. 2022 Nov 16; 2022 Nov 7. PMID: 36343224.
A strategic monitoring approach for learning to improve natural infrastructure.van Rees CB, Naslund L, Hernandez-Abrams DD, McKay SK, Woodson CB, Rosemond A, McFall B, Altman S, Wenger SJ. Sci Total Environ. 2022 Aug 1; 2022 Apr 8. PMID: 35398422.
Glyoxal fixation: an immunohistochemistry assay evaluation.Criswell SL, Altman S, Peeler C, Drake T, Lazar C, Douglas S, DeJarnatt V. J Histotechnol. 2022 Jun; 2021 Dec 8. PMID: 34878359.
The Relation Between Gender Identity and Well-Being.Zitelny H, Dror T, Altman S, Bar-Anan Y. Pers Soc Psychol Bull. 2022 Apr; 2021 Apr 15. PMID: 33858256.
Antisense oligonucleotide gapmers containing phosphoryl guanidine groups reverse MDR1-mediated multiple drug resistance of tumor cells.Kupryushkin MS, Filatov AV, Mironova NL, Patutina OA, Chernikov IV, Chernolovskaya EL, Zenkova MA, Pyshnyi DV, Stetsenko DA, Altman S, Vlassov VV. Mol Ther Nucleic Acids. 2022 Mar 8; 2021 Nov 29. PMID: 34976439.
Improving Oral Health During Pregnancy: A Call to Action.Haber J, Dolce MC, Hartnett E, Altman S, Silk H. J Midwifery Womens Health. 2022 Mar. PMID: 35390222.

2021

A novel virtual hospital at home model during the coronavirus disease 2019 (COVID-19) pandemic.Ryan PP, Hawkins KL, Altman S, Granatowski L, Shy BD, Long J, Hanratty R. Infect Control Hosp Epidemiol. 2021 Sep; 2020 Aug 24. PMID: 32829735.
Inactivating Gene Expression with Antisense Modified Oligonucleotides.Altman S, Angele-Martinez C. Acta Naturae. 2021 Jul-Sep. PMID: 34707901.

2020

Mesyl phosphoramidate backbone modified antisense oligonucleotides targeting miR-21 with enhanced in vivo therapeutic potency.Patutina OA, Gaponova Miroshnichenko SK, Sen'kova AV, Savin IA, Gladkikh DV, Burakova EA, Fokina AA, Maslov MA, Shmendel' EV, Wood MJA, Vlassov VV, Altman S, Stetsenko DA, Zenkova MA. Proc Natl Acad Sci U S A. 2020 Dec 22; 2020 Dec 7. PMID: 33288723.
Liquid drop of DNA libraries reveals total genome information.Terekhov SS, Eliseev IE, Ovchinnikova LA, Kabilov MR, Prjibelski AD, Tupikin AE, Smirnov IV, Belogurov AA Jr, Severinov KV, Lomakin YA, Altman S, Gabibov AG. Proc Natl Acad Sci U S A. 2020 Nov 3; 2020 Oct 21. PMID: 33087570.
Peptide conjugated morpholinos for management of the huanglongbing pathosystem.Sandoval-Mojica AF, Altman S, Hunter WB, Pelz-Stelinski KS. Pest Manag Sci. 2020 Sep; 2020 May 20. PMID: 32358830.
A kinase bioscavenger provides antibiotic resistance by extremely tight substrate binding.Terekhov SS, Mokrushina YA, Nazarov AS, Zlobin A, Zalevsky A, Bourenkov G, Golovin A, Belogurov A Jr, Osterman IA, Kulikova AA, Mitkevich VA, Lou HJ, Turk BE, Wilmanns M, Smirnov IV, Altman S, Gabibov AG. Sci Adv. 2020 Jun; 2020 Jun 24. PMID: 32637600.
Dredging activity and associated sound have negligible effects on adult Atlantic sturgeon migration to spawning habitat in a large coastal river.Balazik M, Barber M, Altman S, Reine K, Katzenmeyer A, Bunch A, Garman G. PLoS One. 2020; 2020 Mar 6. PMID: 32142543.

2019

Comparison of Acute and Chronic Toxicity Laboratory Bioassay Endpoints with Benthic Community Responses in Field-Exposed Contaminated Sediments.Moore DW, Farrar D, Altman S, Bridges TS. Environ Toxicol Chem. 2019 Aug. PMID: 31059149.
Novel Peptide Conjugates of Modified Oligonucleotides for Inhibition of Bacterial RNase P.Novopashina D, Vorobyeva M, Nazarov A, Davydova A, Danilin N, Koroleva L, Matveev A, Bardasheva A, Tikunova N, Kupryushkin M, Pyshnyi D, Altman S, Venyaminova A. Front Pharmacol. 2019; 2019 Jul 19. PMID: 31379580.
Integrating Oral Health Curricula into Midwifery Graduate Programs: Results of a US Survey.Haber J, Dolce MC, Hartnett E, Savageau JA, Altman S, Lange-Kessler J, Silk H. J Midwifery Womens Health. 2019 Jul; 2019 Apr 29. PMID: 31034757.
Mesyl phosphoramidate antisense oligonucleotides as an alternative to phosphorothioates with improved biochemical and biological properties.Miroshnichenko SK, Patutina OA, Burakova EA, Chelobanov BP, Fokina AA, Vlassov VV, Altman S, Zenkova MA, Stetsenko DA. Proc Natl Acad Sci U S A. 2019 Jan 22; 2019 Jan 8. PMID: 30622178.

2018

[Modified Oligonucleotides for Guiding RNA Cleavage Using Bacterial RNase P].Novopashina DS, Nazarov AS, Vorobjeva MA, Kuprushkin MS, Davydova AS, Lomzov AA, Pyshnyi DV, Altman S, Venyaminova AG. Mol Biol (Mosk). 2018 Nov-Dec. PMID: 30633247.
Ultrahigh-throughput functional profiling of microbiota communities.Terekhov SS, Smirnov IV, Malakhova MV, Samoilov AE, Manolov AI, Nazarov AS, Danilov DV, Dubiley SA, Osterman IA, Rubtsova MP, Kostryukova ES, Ziganshin RH, Kornienko MA, Vanyushkina AA, Bukato ON, Ilina EN, Vlasov VV, Severinov KV, Gabibov AG, Altman S. Proc Natl Acad Sci U S A. 2018 Sep 18; 2018 Sep 4. PMID: 30181282.
Data availability, reusability, and analytic reproducibility: evaluating the impact of a mandatory open data policy at the journal Cognition.Hardwicke TE, Mathur MB, MacDonald K, Nilsonne G, Banks GC, Kidwell MC, Hofelich Mohr A, Clayton E, Yoon EJ, Henry Tessler M, Lenne RL, Altman S, Long B, Frank MC. R Soc Open Sci. 2018 Aug; 2018 Aug 15. PMID: 30225032.

2017

Placental and colostral transfer of antibodies reactive with enteropathogenic Escherichia coli intimins α, β, or γ.Altman SPN, Tino-De-Franco M, Carbonare CB, Palmeira P, Carbonare SB. J Pediatr (Rio J). 2017 Nov-Dec; 2017 Mar 19. PMID: 28325675.
Microfluidic droplet platform for ultrahigh-throughput single-cell screening of biodiversity.Terekhov SS, Smirnov IV, Stepanova AV, Bobik TV, Mokrushina YA, Ponomarenko NA, Belogurov AA Jr, Rubtsova MP, Kartseva OV, Gomzikova MO, Moskovtsev AA, Bukatin AS, Dubina MV, Kostryukova ES, Babenko VV, Vakhitova MT, Manolov AI, Malakhova MV, Kornienko MA, Tyakht AV, Vanyushkina AA, Ilina EN, Masson P, Gabibov AG, Altman S. Proc Natl Acad Sci U S A. 2017 Mar 7; 2017 Feb 15. PMID: 28202731.

2016

Aptamers against pathogenic microorganisms.Davydova A, Vorobjeva M, Pyshnyi D, Altman S, Vlassov V, Venyaminova A. Crit Rev Microbiol. 2016 Nov; 2015 Aug 10. PMID: 26258445.
Combinatorial development of antibacterial Zr-Cu-Al-Ag thin film metallic glasses.Liu Y, Padmanabhan J, Cheung B, Liu J, Chen Z, Scanley BE, Wesolowski D, Pressley M, Broadbridge CC, Altman S, Schwarz UD, Kyriakides TR, Schroers J. Sci Rep. 2016 May 27; 2016 May 27. PMID: 27230692.
Should Israel be concerned by the high proportion of medical care paid for privately: comments from a U.S. perspective.Altman S. Isr J Health Policy Res. 2016; 2016 Mar 15. PMID: 26981233.

2015

Targeting protein translation, RNA splicing, and degradation by morpholino-based conjugates in Plasmodium falciparum.Garg A, Wesolowski D, Alonso D, Deitsch KW, Ben Mamoun C, Altman S. Proc Natl Acad Sci U S A. 2015 Sep 22; 2015 Sep 8. PMID: 26351679.
Human RNase P ribonucleoprotein is required for formation of initiation complexes of RNA polymerase III.Serruya R, Orlovetskie N, Reiner R, Dehtiar-Zilber Y, Wesolowski D, Altman S, Jarrous N. Nucleic Acids Res. 2015 Jun 23; 2015 May 7. PMID: 25953854.
Twenty years.Altman S. RNA. 2015 Apr. PMID: 25780119.

2014

Antibiotics present and future.Altman S. FEBS Lett. 2014 Jan 3; 2013 Nov 16. PMID: 24252220.
Federal and state benefits for transition age youth.Altman S, O'Connor S, Anapolsky E, Sexton L. J Pediatr Rehabil Med. 2014. PMID: 24919940.

2013

A peptide-morpholino oligomer conjugate targeting Staphylococcus aureus gyrA mRNA improves healing in an infected mouse cutaneous wound model.Sawyer AJ, Wesolowski D, Gandotra N, Stojadinovic A, Izadjoo M, Altman S, Kyriakides TR. Int J Pharm. 2013 Sep 10; 2013 May 29. PMID: 23727592.
Identification and functional analysis of the primary pantothenate transporter, PfPAT, of the human malaria parasite Plasmodium falciparum.Augagneur Y, Jaubert L, Schiavoni M, Pachikara N, Garg A, Usmani-Brown S, Wesolowski D, Zeller S, Ghosal A, Cornillot E, Said HM, Kumar P, Altman S, Ben Mamoun C. J Biol Chem. 2013 Jul 12; 2013 May 31. PMID: 23729665.
Combined effect of a peptide-morpholino oligonucleotide conjugate and a cell-penetrating peptide as an antibiotic.Wesolowski D, Alonso D, Altman S. Proc Natl Acad Sci U S A. 2013 May 21; 2013 May 6. PMID: 23650357.
The RNA-Protein World.Altman S. RNA. 2013 May. PMID: 23592800.
The economic impact of anastomotic leakage after anterior resections in English NHS hospitals: are we adequately remunerating them?Ashraf SQ, Burns EM, Jani A, Altman S, Young JD, Cunningham C, Faiz O, Mortensen NJ. Colorectal Dis. 2013 Apr. PMID: 23331871.

2012

U.S. basic research: still number one?Altman S. Science. 2012 Sep 28. PMID: 23019630.
A systemic approach to containing health care spending.Emanuel E, Tanden N, Altman S, Armstrong S, Berwick D, de Brantes F, Calsyn M, Chernew M, Colmers J, Cutler D, Daschle T, Egerman P, Kocher B, Milstein A, Oshima Lee E, Podesta JD, Reinhardt U, Rosenthal M, Sharfstein J, Shortell S, Stern A, Orszag PR, Spiro T. N Engl J Med. 2012 Sep 6; 2012 Aug 1. PMID: 22852883.
Gene selective mRNA cleavage inhibits the development of Plasmodium falciparum.Augagneur Y, Wesolowski D, Tae HS, Altman S, Ben Mamoun C. Proc Natl Acad Sci U S A. 2012 Apr 17; 2012 Apr 2. PMID: 22474358.
RNA therapeutics: beyond RNA interference and antisense oligonucleotides.Kole R, Krainer AR, Altman S. Nat Rev Drug Discov. 2012 Jan 20; 2012 Jan 20. PMID: 22262036.

2011

Ribonuclease P.Altman S. Philos Trans R Soc Lond B Biol Sci. 2011 Oct 27. PMID: 21930585.
Basic peptide-morpholino oligomer conjugate that is very effective in killing bacteria by gene-specific and nonspecific modes.Wesolowski D, Tae HS, Gandotra N, Llopis P, Shen N, Altman S. Proc Natl Acad Sci U S A. 2011 Oct 4; 2011 Sep 26. PMID: 21949365.
Consumption of different sources of omega-3 polyunsaturated fatty acids by growing female rats affects long bone mass and microarchitecture.Lukas R, Gigliotti JC, Smith BJ, Altman S, Tou JC. Bone. 2011 Sep; 2011 Jun 6. PMID: 21672645.
RNA binding properties of conserved protein subunits of human RNase P.Reiner R, Alfiya-Mor N, Berrebi-Demma M, Wesolowski D, Altman S, Jarrous N. Nucleic Acids Res. 2011 Jul; 2011 Mar 30. PMID: 21450806.
Inactivation of expression of two genes in Saccharomyces cerevisiae with the external guide sequence methodology.Cheng X, Ko JH, Altman S. RNA. 2011 Mar; 2011 Jan 13. PMID: 21233222.

2010

Morpholino oligonucleotides do not participate perfectly in standard Watson-Crick complexes with RNA.Xiao G, Wesolowski D, Izadjoo M, Altman S. RNA. 2010 Nov; 2010 Sep 3. PMID: 20817753.
Inhibition of gene expression by RNase P.Lundblad EW, Altman S. N Biotechnol. 2010 Jul 31; 2010 Mar 6. PMID: 20211282.
State and federal benefits for children with special healthcare needs.Goldstein KP, Altman S, Zimmerman A. Pediatr Ann. 2010 Apr. PMID: 20411903.
Determination of digestibility, tissue deposition, and metabolism of the omega-3 fatty acid content of krill protein concentrate in growing rats.Bridges KM, Gigliotti JC, Altman S, Jaczynski J, Tou JC. J Agric Food Chem. 2010 Mar 10. PMID: 20131797.
Medicare's opportunity to encourage innovation in health care delivery.Mechanic R, Altman S. N Engl J Med. 2010 Mar 4. PMID: 20200381.
Stent graft versus balloon angioplasty for failing dialysis-access grafts.Haskal ZJ, Trerotola S, Dolmatch B, Schuman E, Altman S, Mietling S, Berman S, McLennan G, Trimmer C, Ross J, Vesely T. N Engl J Med. 2010 Feb 11. PMID: 20147715.

2006

Predictors of relapse in bipolar disorder: A review.Altman S, Haeri S, Cohen LJ, Ten A, Barron E, Galynker II, Duhamel KN. J Psychiatr Pract. 2006 Sep. PMID: 16998415.

2005

Analysis of putative RNase P RNA from orthopoxviruses.Yang L, Wesolowski D, Li Y, Altman S. J Mol Biol. 2005 Dec 2; 2005 Sep 29. PMID: 16253270.
Hugh Dunbar Robertson (1943-2005).Mathews MB, Altman S, McClain WH. RNA. 2005 Dec; 2005 Nov 28. PMID: 30157603.
Regulated expression of functional external guide sequences in mammalian cells using a U6 RNA polymerase III promoter.Kovrigina E, Yang L, Pfund E, Altman S. RNA. 2005 Oct; 2005 Aug 30. PMID: 16131590.
Using ethics to fight bioterrorism.Agre PC, Altman S, Curl RF, Wiesel TN, West-Eberhard MJ. Science. 2005 Aug 12. PMID: 16106523.
RNase P cleaves transient structures in some riboswitches.Altman S, Wesolowski D, Guerrier-Takada C, Li Y. Proc Natl Acad Sci U S A. 2005 Aug 9; 2005 Aug 1. PMID: 16061811.
Masters of DNA.Altman S. J Biol Chem. 2005 Apr 15; 2005 Feb 17. PMID: 15718237.
An open letter to Elias Zerhouni.Altman S, Bassler BL, Beckwith J, Belfort M, Berg HC, Bloom B, Brenchley JE, Campbell A, Collier RJ, Connell N, Cozzarelli NR, Craig NL, Darst S, Ebright RH, Elledge SJ, Falkow S, Galan JE, Gottesman M, Gourse R, Grindley ND, Gross CA, Grossman A, Hochschild A, Howe M, Hurwitz J, Isberg RR, Kaplan S, Kornberg A, Kustu SG, Landick RC, Landy A, Levy SB, Losick R, Long SR, Maloy SR, Mekalanos JJ, Neidhardt FC, Pace NR, Ptashne M, Roberts JW, Roth JR, Rothman-Denes LB, Salyers A, Schaechter M, Shapiro L, Silhavy TJ, Simon MI, Walker G, Yanofsky C, Zinder N. Science. 2005 Mar 4. PMID: 15746409.
Adverse events and preventable adverse events in children.Woods D, Thomas E, Holl J, Altman S, Brennan T. Pediatrics. 2005 Jan. PMID: 15629994.

Karen Anderson

2024

Proof-of-concept studies with a computationally designed M(pro) inhibitor as a synergistic combination regimen alternative to Paxlovid.Papini C, Ullah I, Ranjan AP, Zhang S, Wu Q, Spasov KA, Zhang C, Mothes W, Crawford JM, Lindenbach BD, Uchil PD, Kumar P, Jorgensen WL, Anderson KS. Proc Natl Acad Sci U S A. 2024 Apr 23; 2024 Apr 15. PMID: 38621119.
The electrostatic landscape of MHC-peptide binding revealed using inception networks.Wilson E, Cava JK, Chowell D, Raja R, Mangalaparthi KK, Pandey A, Curtis M, Anderson KS, Singharoy A. Cell Syst. 2024 Mar 25; 2024 Mar 25. PMID: 38554709.
Autoantibodies, antigen-autoantibody complexes and antigens complement CA125 for early detection of ovarian cancer.Young Han C, Bedia JS, Yang WL, Hawley SJ, Bergan L, Hopper M, Celestino J, Guo J, Gornet TG, Soosaipillai A, Yang H, Doskocil SD, Lokshin AE, Handy BC, Diamandis EP, Moore RG, Lu KH, Lu Z, Anderson KS, Drescher CW, Skates SJ, Bast RC Jr. Br J Cancer. 2024 Mar; 2024 Jan 9. PMID: 38195887.
Quantitative assessment of multiple pathogen exposure and immune dynamics at scale.Song L, Rauf F, Hou C-W, Qiu J, Murugan V, Chung Y, Lai H, Adam D, Magee DM, Trivino Soto G, Peterson M, Anderson KS, Rice SG, Readhead B, Park JG, LaBaer J. Microbiol Spectr. 2024 Jan 11; 2023 Dec 8. PMID: 38063388.
Testing Adaptive Therapy Protocols Using Gemcitabine and Capecitabine in a Preclinical Model of Endocrine-Resistant Breast Cancer.Seyedi S, Teo R, Foster L, Saha D, Mina L, Northfelt D, Anderson KS, Shibata D, Gatenby R, Cisneros LH, Troan B, Anderson ARA, Maley CC. Cancers (Basel). 2024 Jan 6; 2024 Jan 6. PMID: 38254748.

2023

Covalent and noncovalent strategies for targeting Lys102 in HIV-1 reverse transcriptase.Prucha GR, Henry S, Hollander K, Carter ZJ, Spasov KA, Jorgensen WL, Anderson KS. Eur J Med Chem. 2023 Dec 15; 2023 Oct 20. PMID: 37883896.
Exploring novel HIV-1 reverse transcriptase inhibitors with drug-resistant mutants: A double mutant surprise.Hollander K, Chan AH, Frey KM, Hunker O, Ippolito JA, Spasov KA, Yeh YJ, Jorgensen WL, Ho YC, Anderson KS. Protein Sci. 2023 Dec. PMID: 37861472.
A High-Throughput, High-Containment Human Primary Epithelial Airway Organ-on-Chip Platform for SARS-CoV-2 Therapeutic Screening.Fisher CR, Mba Medie F, Luu RJ, Gaibler RB, Mulhern TJ, Miller CR, Zhang CJ, Rubio LD, Marr EE, Vijayakumar V, Gabriel EP, Lopez Quezada L, Zhang CH, Anderson KS, Jorgensen WL, Alladina JW, Medoff BD, Borenstein JT, Gard AL. Cells. 2023 Nov 16; 2023 Nov 16. PMID: 37998374.
Examining ways to score the Epidemic-Pandemic Impacts Inventory in parents of young children.Ratcliff CG, Torres D, Anderson KS, Langley HA. Psychol Assess. 2023 Nov. PMID: 37902666.
Testing Adaptive Therapy Protocols using Gemcitabine and Capecitabine on a Mouse Model of Endocrine-Resistant Breast Cancer.Seyedi S, Teo R, Foster L, Saha D, Mina L, Northfelt D, Anderson KS, Shibata D, Gatenby R, Cisneros L, Troan B, Anderson ARA, Maley CC. bioRxiv. 2023 Sep 22; 2023 Sep 22. PMID: 37781632.
Noncanonical HPV carcinogenesis drives radiosensitization of head and neck tumors.Schrank TP, Kothari A, Weir WH, Stepp WH, Rehmani H, Liu X, Wang X, Sewell A, Li X, Tasoulas J, Kim S, Yarbrough G, Xie Y, Flamand Y, Marur S, Hayward MC, Wu D, Burtness B, Anderson KS, Baldwin AS, Yarbrough WG, Issaeva N. Proc Natl Acad Sci U S A. 2023 Aug 8; 2023 Jul 31. PMID: 37523561.
Tackling FGFR3-driven bladder cancer with a promising synergistic FGFR/HDAC targeted therapy.Wang Z, Muthusamy V, Petrylak DP, Anderson KS. NPJ Precis Oncol. 2023 Jul 21; 2023 Jul 21. PMID: 37479885.
Design, synthesis, and biological testing of biphenylmethyloxazole inhibitors targeting HIV-1 reverse transcriptase.Carter ZJ, Hollander K, Spasov KA, Anderson KS, Jorgensen WL. Bioorg Med Chem Lett. 2023 Mar 15; 2023 Mar 3. PMID: 36871704.
Immunogenicity of CRISPR therapeutics-Critical considerations for clinical translation.Ewaisha R, Anderson KS. Front Bioeng Biotechnol. 2023; 2023 Feb 16. PMID: 36873375.
PDJ amplicon in triple negative breast cancer.Roesler AS, Malasi S, Koslosky L, Hartmayer P, Naab TJ, Carter JM, Zahrieh D, Hillman D, Leon-Ferre RA, Couch FJ, Goetz MP, Anderson KS, Pockaj BA, Barrett MT. Sci Rep. 2023 Jan 12; 2023 Jan 12. PMID: 36635351.

2022

Defining the structure-activity relationship for a novel class of allosteric MKP5 inhibitors.Gannam ZTK, Jamali H, Kweon OS, Herrington J, Shillingford SR, Papini C, Gentzel E, Lolis E, Bennett AM, Ellman JA, Anderson KS. Eur J Med Chem. 2022 Dec 5; 2022 Sep 2. PMID: 36116232.
Leveraging patient derived models of FGFR2 fusion positive intrahepatic cholangiocarcinoma to identify synergistic therapies.Lidsky ME, Wang Z, Lu M, Liu A, Hsu SD, McCall SJ, Sheng Z, Granek JA, Owzar K, Anderson KS, Wood KC. NPJ Precis Oncol. 2022 Oct 23; 2022 Oct 23. PMID: 36274097.
Erratum: Exploring APOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.Papini C, Wang Z, Kudalkar SN, Schrank TP, Tang S, Sasaki T, Wu C, Tejada B, Ziegler SJ, Xiong Y, Issaeva N, Yarbrough WG, Anderson KS. iScience. 2022 Oct 21; 2022 Oct 7. PMID: 36248736.
Exploring ABOBEC3A and APOBEC3B substrate specificity and their role in HPV positive head and neck cancer.Papini C, Wang Z, Kudalkar SN, Schrank TP, Tang S, Sasaki T, Wu C, Tejada B, Ziegler SJ, Xiong Y, Issaeva N, Yarbrough WG, Anderson KS. iScience. 2022 Oct 21; 2022 Sep 5. PMID: 36164654.
Development of an x-ray radiography platform to study laser-direct-drive energy coupling at the National Ignition Facility.Ceurvorst L, Theobald W, Rosenberg MJ, Radha PB, Stoeckl C, Betti R, Anderson KS, Marozas JA, Goncharov VN, Campbell EM, Shuldberg CM, Luo RW, Sweet W, Aghaian L, Carlson L, Bachmann B, Döppner T, Hohenberger M, Glize K, Scott RHH, Colaïtis A, Regan SP. Rev Sci Instrum. 2022 Oct 1. PMID: 36319381.
Therapeutic Targeting of FGFR Signaling in Head and Neck Cancer.Wang Z, Anderson KS. Cancer J. 2022 Sep-Oct 01. PMID: 36165723.
APOBEC mutagenesis and selection for NFE2L2 contribute to the origin of lung squamous-cell carcinoma.Cannataro VL, Kudalkar S, Dasari K, Gaffney SG, Lazowski HM, Jackson LK, Yildiz I, Das RK, Gould Rothberg BE, Anderson KS, Townsend JP. Lung Cancer. 2022 Sep; 2022 Jul 9. PMID: 35872531.
An ultra-brief screening scale for pediatric obsessive-compulsive disorder: The OCI-CV-5.Abramovitch A, Abramowitz JS, McKay D, Cham H, Anderson KS, Farrell LJ, Geller DA, Hanna GL, Mathieu S, McGuire JF, Rosenberg DR, Stewart SE, Storch EA, Wilhelm S. J Affect Disord. 2022 Sep 1; 2022 Jun 11. PMID: 35697331.
Using the Biopsychosocial Approach to Identify Factors Associated with Major Depressive Disorder for Individuals with Hypothyroidism.Anderson KS, Howard KJ, Haskard-Zolnierek KB, Pruin J, Deason RG. Issues Ment Health Nurs. 2022 Aug; 2022 Mar 31. PMID: 35358004.
Is 2045 the best we can do? Mitigating the HPV-related oropharyngeal cancer epidemic.Schuman A, Anderson KS, Day AT, Ferrell J, Sturgis EM, Dahlstrom KR. Expert Rev Anticancer Ther. 2022 Jul; 2022 Jun 17. PMID: 35679626.
The feasibility of using an autologous GM-CSF-secreting breast cancer vaccine to induce immunity in patients with stage II-III and metastatic breast cancers.Anderson KS, Erick TK, Chen M, Daley H, Campbell M, Colson Y, Mihm M, Zakka LR, Hopper M, Barry W, Winer EP, Dranoff G, Overmoyer B. Breast Cancer Res Treat. 2022 Jul; 2022 Apr 28. PMID: 35482127.
The OCI-CV-R: A Revision of the Obsessive-Compulsive Inventory - Child Version.Abramovitch A, Abramowitz JS, McKay D, Cham H, Anderson KS, Farrell L, Geller DA, Hanna GL, Mathieu S, McGuire JF, Rosenberg DR, Stewart SE, Storch EA, Wilhelm S. J Anxiety Disord. 2022 Mar; 2022 Jan 15. PMID: 35091252.
Structural Studies and Structure Activity Relationships for Novel Computationally Designed Non-nucleoside Inhibitors and Their Interactions With HIV-1 Reverse Transcriptase.Frey KM, Bertoletti N, Chan AH, Ippolito JA, Bollini M, Spasov KA, Jorgensen WL, Anderson KS. Front Mol Biosci. 2022; 2022 Feb 14. PMID: 35237658.
Long-acting and extended-release implant and nanoformulations with a synergistic antiretroviral two-drug combination controls HIV-1 infection in a humanized mouse model.Beloor J, Kudalkar SN, Buzzelli G, Yang F, Mandl HK, Rajashekar JK, Spasov KA, Jorgensen WL, Saltzman WM, Anderson KS, Kumar P. Bioeng Transl Med. 2022 Jan; 2021 Jun 26. PMID: 35079625.
Beyond Sequencing: Prioritizing and Delivering Neoantigens for Cancer Vaccines.Roesler AS, Anderson KS. Methods Mol Biol. 2022. PMID: 34914074.

2021

Pitch and Rhythm Perception and Verbal Short-Term Memory in Acute Traumatic Brain Injury.Anderson KS, Gosselin N, Sadikot AF, Laguë-Beauvais M, Kang ESH, Fogarty AE, Marcoux J, Dagher J, de Guise E. Brain Sci. 2021 Sep 3; 2021 Sep 3. PMID: 34573194.
Experimentally Inferred Fusion Yield Dependencies of OMEGA Inertial Confinement Fusion Implosions.Lees A, Betti R, Knauer JP, Gopalaswamy V, Patel D, Woo KM, Anderson KS, Campbell EM, Cao D, Carroll-Nellenback J, Epstein R, Forrest C, Goncharov VN, Harding DR, Hu SX, Igumenshchev IV, Janezic RT, Mannion OM, Radha PB, Regan SP, Shvydky A, Shah RC, Shmayda WT, Stoeckl C, Theobald W, Thomas C. Phys Rev Lett. 2021 Sep 3. PMID: 34533333.
Screening for HPV-related oropharyngeal, anal, and penile cancers in middle-aged men: Initial report from the HOUSTON clinical trial.Dahlstrom KR, Anderson KS, Guo M, Kwon MC, Messick CA, Pettaway CA, Asomaning N, Hopper M, Price A, Xu L, Day AT, Gillenwater AM, Sturgis EM. Oral Oncol. 2021 Sep; 2021 Jun 26. PMID: 34182223.
Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency.Zhang CH, Spasov KA, Reilly RA, Hollander K, Stone EA, Ippolito JA, Liosi ME, Deshmukh MG, Tirado-Rives J, Zhang S, Liang Z, Miller SJ, Isaacs F, Lindenbach BD, Anderson KS, Jorgensen WL. ACS Med Chem Lett. 2021 Aug 12; 2021 Jul 14. PMID: 34408808.
Structure-guided design of a perampanel-derived pharmacophore targeting the SARS-CoV-2 main protease.Deshmukh MG, Ippolito JA, Zhang CH, Stone EA, Reilly RA, Miller SJ, Jorgensen WL, Anderson KS. Structure. 2021 Aug 5; 2021 Jun 22. PMID: 34161756.
Measuring nonhomologous end-joining, homologous recombination and alternative end-joining simultaneously at an endogenous locus in any transfectable human cell.Hussain SS, Majumdar R, Moore GM, Narang H, Buechelmaier ES, Bazil MJ, Ravindran PT, Leeman JE, Li Y, Jalan M, Anderson KS, Farina A, Soni R, Mohibullah N, Hamzic E, Rong-Mullins X, Sifuentes C, Damerla RR, Viale A, Powell SN, Higginson DS. Nucleic Acids Res. 2021 Jul 21. PMID: 33877327.
Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation.Wu K, Wu H, Lyu W, Kim Y, Furdui CM, Anderson KS, Koleske AJ. J Biol Chem. 2021 Jul; 2021 Jun 16. PMID: 34144039.
Unique evolutionary trajectories of breast cancers with distinct genomic and spatial heterogeneity.Phung TN, Webster TH, Lenkiewicz E, Malasi S, Andreozzi M, McCullough AE, Anderson KS, Pockaj BA, Wilson MA, Barrett MT. Sci Rep. 2021 May 19; 2021 May 19. PMID: 34011996.
Public health impact of delaying second dose of BNT162b2 or mRNA-1273 covid-19 vaccine: simulation agent based modeling study.Romero-Brufau S, Chopra A, Ryu AJ, Gel E, Raskar R, Kremers W, Anderson KS, Subramanian J, Krishnamurthy B, Singh A, Pasupathy K, Dong Y, O'Horo JC, Wilson WR, Mitchell O, Kingsley TC. BMJ. 2021 May 12; 2021 May 12. PMID: 33980718.
Potent Noncovalent Inhibitors of the Main Protease of SARS-CoV-2 from Molecular Sculpting of the Drug Perampanel Guided by Free Energy Perturbation Calculations.Zhang CH, Stone EA, Deshmukh M, Ippolito JA, Ghahremanpour MM, Tirado-Rives J, Spasov KA, Zhang S, Takeo Y, Kudalkar SN, Liang Z, Isaacs F, Lindenbach B, Miller SJ, Anderson KS, Jorgensen WL. ACS Cent Sci. 2021 Mar 24; 2021 Feb 22. PMID: 33786375.
Total predicted MHC-I epitope load is inversely associated with population mortality from SARS-CoV-2.Wilson EA, Hirneise G, Singharoy A, Anderson KS. Cell Rep Med. 2021 Mar 16; 2021 Feb 25. PMID: 33649748.
Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead.Ippolito JA, Niu H, Bertoletti N, Carter ZJ, Jin S, Spasov KA, Cisneros JA, Valhondo M, Cutrona KJ, Anderson KS, Jorgensen WL. ACS Med Chem Lett. 2021 Feb 11; 2021 Jan 6. PMID: 33603971.

2020

Global Genome Demethylation Causes Transcription-Associated DNA Double Strand Breaks in HPV-Associated Head and Neck Cancer Cells.Hajek M, Biktasova A, Sewell A, Gary C, Cantalupo P, Anderson KS, Yarbrough WG, Issaeva N. Cancers (Basel). 2020 Dec 23; 2020 Dec 23. PMID: 33374558.
Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2.Ghahremanpour MM, Tirado-Rives J, Deshmukh M, Ippolito JA, Zhang CH, Cabeza de Vaca I, Liosi ME, Anderson KS, Jorgensen WL. ACS Med Chem Lett. 2020 Dec 10; 2020 Oct 25. PMID: 33324471.
Biomarkers and Strategies for Early Detection of Ovarian Cancer.Bast RC Jr, Lu Z, Han CY, Lu KH, Anderson KS, Drescher CW, Skates SJ. Cancer Epidemiol Biomarkers Prev. 2020 Dec; 2020 Oct 13. PMID: 33051337.
Autoantibodies in Early Detection of Breast Cancer.Rauf F, Anderson KS, LaBaer J. Cancer Epidemiol Biomarkers Prev. 2020 Dec; 2020 Sep 29. PMID: 32994341.
Post-Catalytic Complexes with Emtricitabine or Stavudine and HIV-1 Reverse Transcriptase Reveal New Mechanistic Insights for Nucleotide Incorporation and Drug Resistance.Bertoletti N, Chan AH, Schinazi RF, Anderson KS. Molecules. 2020 Oct 21; 2020 Oct 21. PMID: 33096918.
Structural investigation of 2-naphthyl phenyl ether inhibitors bound to WT and Y181C reverse transcriptase highlights key features of the NNRTI binding site.Duong VN, Ippolito JA, Chan AH, Lee WG, Spasov KA, Jorgensen WL, Anderson KS. Protein Sci. 2020 Sep; 2020 Aug 5. PMID: 32643196.
Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2.Ghahremanpour MM, Tirado-Rives J, Deshmukh M, Ippolito JA, Zhang CH, de Vaca IC, Liosi ME, Anderson KS, Jorgensen WL. bioRxiv. 2020 Aug 28; 2020 Aug 28. PMID: 32869018.
An allosteric site on MKP5 reveals a strategy for small-molecule inhibition.Gannam ZTK, Min K, Shillingford SR, Zhang L, Herrington J, Abriola L, Gareiss PC, Pantouris G, Tzouvelekis A, Kaminski N, Zhang X, Yu J, Jamali H, Ellman JA, Lolis E, Anderson KS, Bennett AM. Sci Signal. 2020 Aug 25; 2020 Aug 25. PMID: 32843541.
Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitors.Ruiz VG, Czyzyk DJ, Kumar VP, Jorgensen WL, Anderson KS. Bioorg Med Chem Lett. 2020 Aug 15; 2020 May 30. PMID: 32631514.
Unique genomic and neoepitope landscapes across tumors: a study across time, tissues, and space within a single lynch syndrome patient.Phung TN, Lenkiewicz E, Malasi S, Sharma A, Anderson KS, Wilson MA, Pockaj BA, Barrett MT. Sci Rep. 2020 Jul 22; 2020 Jul 22. PMID: 32699259.
Change in 21-gene Recurrence Score result after exposure to neo-adjuvant endocrine therapy in patients with operable breast cancer.Hilal T, Mi L, Ertz-Archambault NM, Almquist DR, Anderson KS, Gray RJ, Pockaj BA, Northfelt DW. Breast J. 2020 Jul; 2019 Dec 26. PMID: 31876083.
Identifying the role of PrimPol in TDF-induced toxicity and implications of its loss of function mutation in an HIV+ patient.Duong VN, Zhou L, Martínez-Jiménez MI, He L, Cosme M, Blanco L, Paintsil E, Anderson KS. Sci Rep. 2020 Jun 9; 2020 Jun 9. PMID: 32518272.
Structure-Guided Identification of DNMT3B Inhibitors.Newton AS, Faver JC, Micevic G, Muthusamy V, Kudalkar SN, Bertoletti N, Anderson KS, Bosenberg MW, Jorgensen WL. ACS Med Chem Lett. 2020 May 14; 2020 Feb 7. PMID: 32435413.
Depomedroxyprogesterone acetate therapy for hot flashes in survivors of breast cancer: no unfavorable impact on recurrence and survival.Ertz-Archambault NM, Rogoff LB, Kosiorek HE, Ernst BJ, Anderson KS, Pockaj BA, Gray RJ, Northfelt DW. Support Care Cancer. 2020 May; 2019 Aug 11. PMID: 31402403.

2019

Structure activity relationship towards design of cryptosporidium specific thymidylate synthase inhibitors.Czyzyk DJ, Valhondo M, Deiana L, Tirado-Rives J, Jorgensen WL, Anderson KS. Eur J Med Chem. 2019 Dec 1; 2019 Sep 4. PMID: 31536894.
Weakly immunogenic CRISPR therapies.Wilson EA, Anderson KS. Nat Biomed Eng. 2019 Oct. PMID: 31591524.
Structural insights into the recognition of nucleoside reverse transcriptase inhibitors by HIV-1 reverse transcriptase: First crystal structures with reverse transcriptase and the active triphosphate forms of lamivudine and emtricitabine.Bertoletti N, Chan AH, Schinazi RF, Yin YW, Anderson KS. Protein Sci. 2019 Sep; 2019 Aug 6. PMID: 31301259.
Molecular and cellular studies evaluating a potent 2-cyanoindolizine catechol diether NNRTI targeting wildtype and Y181C mutant HIV-1 reverse transcriptase.Sasaki T, Gannam ZTK, Kudalkar SN, Frey KM, Lee WG, Spasov KA, Jorgensen WL, Anderson KS. Bioorg Med Chem Lett. 2019 Aug 15; 2019 Jun 26. PMID: 31281023.
Personalized circulating tumor DNA analysis to detect residual disease after neoadjuvant therapy in breast cancer.McDonald BR, Contente-Cuomo T, Sammut SJ, Odenheimer-Bergman A, Ernst B, Perdigones N, Chin SF, Farooq M, Mejia R, Cronin PA, Anderson KS, Kosiorek HE, Northfelt DW, McCullough AE, Patel BK, Weitzel JN, Slavin TP, Caldas C, Pockaj BA, Murtaza M. Sci Transl Med. 2019 Aug 7. PMID: 31391323.
Understanding the structural basis of species selective, stereospecific inhibition for Cryptosporidium and human thymidylate synthase.Czyzyk DJ, Valhondo M, Jorgensen WL, Anderson KS. FEBS Lett. 2019 Aug; 2019 Jun 18. PMID: 31172516.
The burden of 14 hr-HPV genotypes in women attending routine cervical cancer screening in 20 states of Mexico: a cross-sectional study.Campos-Romero A, Anderson KS, Longatto-Filho A, Luna-Ruiz Esparza MA, Morán-Portela DJ, Castro-Menéndez JA, Moreno-Camacho JL, Calva-Espinosa DY, Acosta-Alfaro MA, Meynard-Mejía FA, Muñoz-Gaitán M, Alcántar-Fernández J. Sci Rep. 2019 Jul 12; 2019 Jul 12. PMID: 31300693.
Structural and pharmacological evaluation of a novel non-nucleoside reverse transcriptase inhibitor as a promising long acting nanoformulation for treating HIV.Kudalkar SN, Ullah I, Bertoletti N, Mandl HK, Cisneros JA, Beloor J, Chan AH, Quijano E, Saltzman WM, Jorgensen WL, Kumar P, Anderson KS. Antiviral Res. 2019 Jul; 2019 Apr 26. PMID: 31034849.
Novel allosteric covalent inhibitors of bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa identified by virtual screening.Ruiz V, Czyzyk DJ, Valhondo M, Jorgensen WL, Anderson KS. Bioorg Med Chem Lett. 2019 Jun 1; 2019 Mar 20. PMID: 30929953.
APOBEC-induced mutations and their cancer effect size in head and neck squamous cell carcinoma.Cannataro VL, Gaffney SG, Sasaki T, Issaeva N, Grewal NKS, Grandis JR, Yarbrough WG, Burtness B, Anderson KS, Townsend JP. Oncogene. 2019 May; 2019 Jan 15. PMID: 30647454.
Multifunctional CRISPR-Cas9 with engineered immunosilenced human T cell epitopes.Ferdosi SR, Ewaisha R, Moghadam F, Krishna S, Park JG, Ebrahimkhani MR, Kiani S, Anderson KS. Nat Commun. 2019 Apr 23; 2019 Apr 23. PMID: 31015529.
The neoepitope landscape of breast cancer: implications for immunotherapy.Narang P, Chen M, Sharma AA, Anderson KS, Wilson MA. BMC Cancer. 2019 Mar 4; 2019 Mar 4. PMID: 30832597.
HPV: Immunology lessons from an ancient oncotarget.Krishna S, Anderson KS. Oncotarget. 2019 Feb 12; 2019 Feb 12. PMID: 30863487.
The FGFR1 V561M Gatekeeper Mutation Drives AZD4547 Resistance through STAT3 Activation and EMT.Ryan MR, Sohl CD, Luo B, Anderson KS. Mol Cancer Res. 2019 Feb; 2018 Sep 26. PMID: 30257990.
Tripled yield in direct-drive laser fusion through statistical modelling.Gopalaswamy V, Betti R, Knauer JP, Luciani N, Patel D, Woo KM, Bose A, Igumenshchev IV, Campbell EM, Anderson KS, Bauer KA, Bonino MJ, Cao D, Christopherson AR, Collins GW, Collins TJB, Davies JR, Delettrez JA, Edgell DH, Epstein R, Forrest CJ, Froula DH, Glebov VY, Goncharov VN, Harding DR, Hu SX, Jacobs-Perkins DW, Janezic RT, Kelly JH, Mannion OM, Maximov A, Marshall FJ, Michel DT, Miller S, Morse SFB, Palastro J, Peebles J, Radha PB, Regan SP, Sampat S, Sangster TC, Sefkow AB, Seka W, Shah RC, Shmyada WT, Shvydky A, Stoeckl C, Solodov AA, Theobald W, Zuegel JD, Johnson MG, Petrasso RD, Li CK, Frenje JA. Nature. 2019 Jan; 2019 Jan 30. PMID: 30700868.
A Noninvasive Blood-based Combinatorial Proteomic Biomarker Assay to Detect Breast Cancer in Women over age 50 with BI-RADS 3, 4, or 5 Assessment.Henderson MC, Silver M, Tran Q, Letsios EE, Mulpuri R, Reese DE, Lourenco AP, LaBaer J, Anderson KS, Alpers J, Costantini C, Rohatgi N, Ali H, Baker K, Northfelt DW, Ghosh K, Grobmyer SR, Polen W, Wolf JK. Clin Cancer Res. 2019 Jan 1; 2018 Sep 5. PMID: 30185421.

2018

Lost in the crowd: identifying targetable MHC class I neoepitopes for cancer immunotherapy.Wilson EA, Anderson KS. Expert Rev Proteomics. 2018 Dec; 2018 Nov 14. PMID: 30408427.
Human Papilloma Virus Specific Immunogenicity and Dysfunction of CD8(+) T Cells in Head and Neck Cancer.Krishna S, Ulrich P, Wilson E, Parikh F, Narang P, Yang S, Read AK, Kim-Schulze S, Park JG, Posner M, Wilson Sayres MA, Sikora A, Anderson KS. Cancer Res. 2018 Nov 1; 2018 Aug 28. PMID: 30154146.
Eccrine Sweat as a Biofluid for Profiling Immune Biomarkers.Katchman BA, Zhu M, Blain Christen J, Anderson KS. Proteomics Clin Appl. 2018 Nov; 2018 Jun 28. PMID: 29882373.
DRONE: Direct Tracking of DNA Cytidine Deamination and Other DNA Modifying Activities.Sasaki T, Kudalkar SN, Bertoletti N, Anderson KS. Anal Chem. 2018 Oct 16; 2018 Sep 28. PMID: 30256094.
A compact, low-cost, quantitative and multiplexed fluorescence detection platform for point-of-care applications.Obahiagbon U, Smith JT, Zhu M, Katchman BA, Arafa H, Anderson KS, Blain Christen JM. Biosens Bioelectron. 2018 Oct 15; 2018 Apr 4. PMID: 29894852.
JAK2 and PD-L1 Amplification Enhance the Dynamic Expression of PD-L1 in Triple-negative Breast Cancer.Chen M, Pockaj B, Andreozzi M, Barrett MT, Krishna S, Eaton S, Niu R, Anderson KS. Clin Breast Cancer. 2018 Oct; 2018 May 26. PMID: 29933930.
Reply to Pandey et al.: Understanding the efficacy of a potential antiretroviral drug candidate in humanized mouse model of HIV infection.Kudalkar SN, Beloor J, Quijano E, Spasov KA, Lee WG, Cisneros JA, Saltzman WM, Kumar P, Jorgensen WL, Anderson KS. Proc Natl Acad Sci U S A. 2018 Aug 28; 2018 Aug 10. PMID: 30097540.
Tumor-associated autoantibodies as early detection markers for ovarian cancer? A prospective evaluation.Kaaks R, Fortner RT, Hüsing A, Barrdahl M, Hopper M, Johnson T, Tjønneland A, Hansen L, Overvad K, Fournier A, Boutron-Ruault MC, Kvaskoff M, Dossus L, Johansson M, Boeing H, Trichopoulou A, Benetou V, La Vecchia C, Sieri S, Mattiello A, Palli D, Tumino R, Matullo G, Onland-Moret NC, Gram IT, Weiderpass E, Sánchez MJ, Navarro Sanchez C, Duell EJ, Ardanaz E, Larranaga N, Lundin E, Idahl A, Jirström K, Nodin B, Travis RC, Riboli E, Merritt M, Aune D, Terry K, Cramer DW, Anderson KS. Int J Cancer. 2018 Aug 1; 2018 Mar 8. PMID: 29473162.
The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers.Barrett MT, Lenkiewicz E, Malasi S, Basu A, Yearley JH, Annamalai L, McCullough AE, Kosiorek HE, Narang P, Wilson Sayres MA, Chen M, Anderson KS, Pockaj BA. Breast Cancer Res. 2018 Jul 11; 2018 Jul 11. PMID: 29996881.
Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent.Yang M, Wu H, Chu J, Gabriel LA, Kim Y, Anderson KS, Furdui CM, Bierbach U. Chem Commun (Camb). 2018 Jul 11; 2018 Jun 19. PMID: 29915817.
Activity and fidelity of human DNA polymerase α depend on primer structure.Baranovskiy AG, Duong VN, Babayeva ND, Zhang Y, Pavlov YI, Anderson KS, Tahirov TH. J Biol Chem. 2018 May 4; 2018 Mar 19. PMID: 29555682.
Pre-diagnostic dynamic HPV16 IgG seropositivity and risk of oropharyngeal cancer: Methodologic issues.Anderson KS, Mork J, Langseth H, Wallstrom G. Oral Oncol. 2018 May; 2018 Mar 30. PMID: 29606498.
Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies.Ziegler SJ, Liu C, Landau M, Buzovetsky O, Desimmie BA, Zhao Q, Sasaki T, Burdick RC, Pathak VK, Anderson KS, Xiong Y. PLoS One. 2018; 2018 Mar 29. PMID: 29596531.
An Automated Microfluidic Assay for Photonic Crystal Enhanced Detection and Analysis of an Antiviral Antibody Cancer Biomarker in Serum.Race CM, Kwon LE, Foreman MT, Huang Q, Inan H, Kesiraju S, Le P, Lim SJ, Smith AM, Zangar RC, Demirci U, Anderson KS, Cunningham BT. IEEE Sens J. 2018 Feb 15; 2017 Nov 24. PMID: 29881332.
Modeling the Subclonal Evolution of Cancer Cell Populations.Chowell D, Napier J, Gupta R, Anderson KS, Maley CC, Sayres MAW. Cancer Res. 2018 Feb 1; 2017 Nov 29. PMID: 29187407.
From in silico hit to long-acting late-stage preclinical candidate to combat HIV-1 infection.Kudalkar SN, Beloor J, Quijano E, Spasov KA, Lee WG, Cisneros JA, Saltzman WM, Kumar P, Jorgensen WL, Anderson KS. Proc Natl Acad Sci U S A. 2018 Jan 23; 2017 Dec 26. PMID: 29279368.
Stage Dependence, Cell-Origin Independence, and Prognostic Capacity of Serum Glycan Fucosylation, β1-4 Branching, β1-6 Branching, and α2-6 Sialylation in Cancer.Ferdosi S, Rehder DS, Maranian P, Castle EP, Ho TH, Pass HI, Cramer DW, Anderson KS, Fu L, Cole DEC, Le T, Wu X, Borges CR. J Proteome Res. 2018 Jan 5; 2017 Nov 21. PMID: 29129073.

2017

Diagnostic accuracy of serum antibodies to human papillomavirus type 16 early antigens in the detection of human papillomavirus-related oropharyngeal cancer.Dahlstrom KR, Anderson KS, Field MS, Chowell D, Ning J, Li N, Wei Q, Li G, Sturgis EM. Cancer. 2017 Dec 15; 2017 Sep 12. PMID: 28898394.
Discussion of: "The success of sentinel lymph node biopsy after neoadjuvant therapy: A single institution review".Chang JM, Kosiorek HE, Wasif N, Gray RJ, Stucky CH, Northfelt DW, Anderson KS, McCullough AE, Tolgay Ocal I, Pockaj BA. Am J Surg. 2017 Dec; 2017 Sep 30. PMID: 29037421.
The success of sentinel lymph node biopsy after neoadjuvant therapy: A single institution review.Chang JM, Kosiorek HE, Wasif N, Gray RJ, Stucky CH, Northfelt DW, Anderson KS, McCullough AE, Ocal IT, Pockaj BA. Am J Surg. 2017 Dec; 2017 Sep 18. PMID: 28943062.
Development and validation of a novel clinical fluorescence in situ hybridization assay to detect JAK2 and PD-L1 amplification: a fluorescence in situ hybridization assay for JAK2 and PD-L1 amplification.Chen M, Andreozzi M, Pockaj B, Barrett MT, Ocal IT, McCullough AE, Linnaus ME, Chang JM, Yearley JH, Annamalai L, Anderson KS. Mod Pathol. 2017 Nov; 2017 Jul 28. PMID: 28752839.
Pre-diagnostic dynamic HPV16 IgG seropositivity and risk of oropharyngeal cancer.Anderson KS, Wallstrom G, Langseth H, Posner M, Cheng JN, Alam R, Chowell D, Furre IE, Mork J. Oral Oncol. 2017 Oct; 2017 Sep 1. PMID: 28939065.
Classifying the evolutionary and ecological features of neoplasms.Maley CC, Aktipis A, Graham TA, Sottoriva A, Boddy AM, Janiszewska M, Silva AS, Gerlinger M, Yuan Y, Pienta KJ, Anderson KS, Gatenby R, Swanton C, Posada D, Wu CI, Schiffman JD, Hwang ES, Polyak K, Anderson ARA, Brown JS, Greaves M, Shibata D. Nat Rev Cancer. 2017 Oct; 2017 Sep 15. PMID: 28912577.
Covalent inhibitors for eradication of drug-resistant HIV-1 reverse transcriptase: From design to protein crystallography.Chan AH, Lee WG, Spasov KA, Cisneros JA, Kudalkar SN, Petrova ZO, Buckingham AB, Anderson KS, Jorgensen WL. Proc Natl Acad Sci U S A. 2017 Sep 5; 2017 Aug 21. PMID: 28827354.
Serum Immune Profiling for Early Detection of Cervical Disease.Ewaisha R, Panicker G, Maranian P, Unger ER, Anderson KS. Theranostics. 2017; 2017 Aug 23. PMID: 29109779.
NeoPalAna: Neoadjuvant Palbociclib, a Cyclin-Dependent Kinase 4/6 Inhibitor, and Anastrozole for Clinical Stage 2 or 3 Estrogen Receptor-Positive Breast Cancer.Ma CX, Gao F, Luo J, Northfelt DW, Goetz M, Forero A, Hoog J, Naughton M, Ademuyiwa F, Suresh R, Anderson KS, Margenthaler J, Aft R, Hobday T, Moynihan T, Gillanders W, Cyr A, Eberlein TJ, Hieken T, Krontiras H, Guo Z, Lee MV, Spies NC, Skidmore ZL, Griffith OL, Griffith M, Thomas S, Bumb C, Vij K, Bartlett CH, Koehler M, Al-Kateb H, Sanati S, Ellis MJ. Clin Cancer Res. 2017 Aug 1; 2017 Mar 7. PMID: 28270497.
Autoantibody biomarkers for the detection of serous ovarian cancer.Katchman BA, Chowell D, Wallstrom G, Vitonis AF, LaBaer J, Cramer DW, Anderson KS. Gynecol Oncol. 2017 Jul; 2017 Apr 18. PMID: 28427776.
Isolation, Detection, and Quantification of Cancer Biomarkers in HPV-Associated Malignancies.Inan H, Wang S, Inci F, Baday M, Zangar R, Kesiraju S, Anderson KS, Cunningham BT, Demirci U. Sci Rep. 2017 Jun 12; 2017 Jun 12. PMID: 28607383.

Warren Andiman

2020

Where Have All the "AIDS Babies" Gone? A Historical Memoir of the Pediatric AIDS Epidemic in New Haven and its Eventual Eradication.Andiman WA. Yale J Biol Med. 2020 Sep; 2020 Sep 30. PMID: 33005128.

2016

Macular Star and Central Visual Loss: Two Pediatric Cases.Nickerson TE, Oliveira CR, Lesser RL, Andiman WA. Clin Pediatr (Phila). 2016 May; 2015 Aug 16. PMID: 26283218.

2012

Chronic kidney disease associated with perinatal HIV infection in children and adolescents.Purswani MU, Chernoff MC, Mitchell CD, Seage GR 3rd, Zilleruelo G, Abitbol C, Andiman WA, Kaiser KA, Spiegel H, Oleske JM. Pediatr Nephrol. 2012 Jun; 2012 Feb 26. PMID: 22366874.
Seroepidemiology of WU polyomavirus among children exposed perinatally to HIV-1.Miller MA, Weibel C, Kahn JS, Andiman WA. J Med Virol. 2012 Feb. PMID: 22170536.

2011

Transition from pediatric to adult healthcare services for young adults with chronic illnesses: the special case of human immunodeficiency virus infection.Andiman WA. J Pediatr. 2011 Nov; 2011 Aug 24. PMID: 21868035.

2010

Antibiotic resistance among pathogens causing disease in Jamaican children with HIV/AIDS.Byam PR, Pierre RB, Christie CD, Andiman WA, Pettigrew M. West Indian Med J. 2010 Jul. PMID: 21355513.

2009

We never thought this would happen: transitioning care of adolescents with perinatally acquired HIV infection from pediatrics to internal medicine.Vijayan T, Benin AL, Wagner K, Romano S, Andiman WA. AIDS Care. 2009 Oct. PMID: 20024697.
Incidence of persistent renal dysfunction in human immunodeficiency virus-infected children: associations with the use of antiretrovirals, and other nephrotoxic medications and risk factors.Andiman WA, Chernoff MC, Mitchell C, Purswani M, Oleske J, Williams PL, Spiegel H, Gona P, Seage GR 3rd. Pediatr Infect Dis J. 2009 Jul. PMID: 19561425.
Update on successes and challenges regarding mother-to-child transmission of HIV.Paintsil E, Andiman WA. Curr Opin Pediatr. 2009 Feb. PMID: 19242245.

2008

Absolute CD4+ T-lymphocyte count as a surrogate marker of pediatric human immunodeficiency virus disease progression.Paintsil E, Ghebremichael M, Romano S, Andiman WA. Pediatr Infect Dis J. 2008 Jul. PMID: 18520446.

2007

Care and management of the infant of the HIV-1-infected mother.Paintsil E, Andiman WA. Semin Perinatol. 2007 Apr. PMID: 17462496.

2006

Virologic and host characteristics of human immunodeficiency virus type 1-infected pediatric long term survivors.Alexander L, Cuchura L, Simpson BJ, Andiman WA. Pediatr Infect Dis J. 2006 Feb. PMID: 16462290.

2005

Complex determinants in human immunodeficiency virus type 1 envelope gp120 mediate CXCR4-dependent infection of macrophages.Ghaffari G, Tuttle DL, Briggs D, Burkhardt BR, Bhatt D, Andiman WA, Sleasman JW, Goodenow MM. J Virol. 2005 Nov. PMID: 16227248.

2002

Inhibition of human immunodeficiency virus type 1 (HIV-1) replication by a two-amino-acid insertion in HIV-1 Vif from a nonprogressing mother and child.Alexander L, Aquino-DeJesus MJ, Chan M, Andiman WA. J Virol. 2002 Oct. PMID: 12239333.
Increased replication of non-syncytium-inducing HIV type 1 isolates in monocyte-derived macrophages is linked to advanced disease in infected children.Tuttle DL, Anders CB, Aquino-De Jesus MJ, Poole PP, Lamers SL, Briggs DR, Pomeroy SM, Alexander L, Peden KW, Andiman WA, Sleasman JW, Goodenow MM. AIDS Res Hum Retroviruses. 2002 Mar 20. PMID: 11897037.
Transmission of HIV-1 from mother to infant.Andiman WA. Curr Opin Pediatr. 2002 Feb. PMID: 11880739.

2000

Prospective cohort study of children born to human immunodeficiency virus-infected mothers, 1985 through 1997: trends in the risk of vertical transmission, mortality and acquired immunodeficiency syndrome indicator diseases in the era before highly active antiretroviral therapy.Simpson BJ, Shapiro ED, Andiman WA. Pediatr Infect Dis J. 2000 Jul. PMID: 10917219.
Genetically and epidemiologically related "non-syncytium-inducing" isolates of HIV-1 display heterogeneous growth patterns in macrophages.Aquino-De Jesus MJ, Anders C, Miller G, Sleasman JW, Goodenow MM, Andiman WA. J Med Virol. 2000 Jun. PMID: 10797371.

1999

Association between the biological characteristics of HIV-1, vertical transmission of infection and clinical progression of pediatric disease.Andiman WA. Curr Opin Infect Dis. 1999 Jun. PMID: 17035786.

1998

Medical management of the pregnant woman infected with human immunodeficiency virus type 1 and her child.Andiman WA. Semin Perinatol. 1998 Feb. PMID: 9523401.

1997

Reduction in the risk of vertical transmission of HIV-1 associated with treatment of pregnant women with orally administered zidovudine alone.Simpson BJ, Shapiro ED, Andiman WA. J Acquir Immune Defic Syndr Hum Retrovirol. 1997 Feb 1. PMID: 9052723.

1996

Invasive pneumococcal infections in children infected with HIV are not associated with splenic dysfunction.Andiman WA, Simpson J, Holtkamp C, Pearson HA. AIDS Patient Care STDS. 1996 Dec. PMID: 11361548.
Development of a prognosis-based clinical staging system for infants infected with human immunodeficiency virus.Forsyth BW, Andiman WA, O'Connor T. J Pediatr. 1996 Nov. PMID: 8917228.
A reversible posterior leukoencephalopathy syndrome.Kahn JS, Romano S, Andiman WA. N Engl J Med. 1996 Jun 27. PMID: 8637527.
Syncytium-inhibiting and neutralizing activity in maternal sera fail to prevent vertical transmission of human immunodeficiency virus type 1.Bal AK, Miller G, Viscarello R, Andiman WA. Pediatr Infect Dis J. 1996 Apr. PMID: 8866800.

1994

Invasive bacterial infections in children born to women infected with human immunodeficiency virus type 1.Andiman WA, Mezger J, Shapiro E. J Pediatr. 1994 Jun. PMID: 8201465.
Difficulties in assigning human immunodeficiency virus-1 infection and seroreversion status in a cohort of HIV-exposed in children using serologic criteria established by the Centers for Disease Control and Prevention.Simpson BJ, Andiman WA. Pediatrics. 1994 May. PMID: 8165094.

1993

Quantitative leukoviremia and immune complex-dissociated antigenemia as predictors of infection status in children born to mothers infected with human immunodeficiency virus type 1.Ikeda MK, Andiman WA, Mezger JL, Shapiro ED, Miller G. J Pediatr. 1993 Apr. PMID: 8463895.

1992

Predictive value of the human immunodeficiency virus 1 antigen test in children born to infected mothers.Andiman WA, Silva TJ, Shapiro ED, O'Connor T, Olson B. Pediatr Infect Dis J. 1992 Jun. PMID: 1608678.

1991

Frequency of twinning in paediatric HIV infection.McNamara JG, Katz BZ, Andiman WA, Johnson GM. Lancet. 1991 Aug 17. PMID: 1678113.
Organism-specific antibody indices, the cerebrospinal fluid-immunoglobulin index and other tools: a clinician's guide to the etiologic diagnosis of central nervous system infection.Andiman WA. Pediatr Infect Dis J. 1991 Jul. PMID: 1876463.
Relation between HIV-1 syncytium inhibition antibodies and clinical outcome in children.Brenner TJ, Dahl KE, Olson B, Miller G, Andiman WA. Lancet. 1991 Apr 27. PMID: 1673167.

1990

Rate of transmission of human immunodeficiency virus type 1 infection from mother to child and short-term outcome of neonatal infection. Results of a prospective cohort study.Andiman WA, Simpson BJ, Olson B, Dember L, Silva TJ, Miller G. Am J Dis Child. 1990 Jul. PMID: 2113349.

Janet Brandsma

2014

Methylation of twelve CpGs in human papillomavirus type 16 (HPV16) as an informative biomarker for the triage of women positive for HPV16 infection.Brandsma JL, Harigopal M, Kiviat NB, Sun Y, Deng Y, Zelterman D, Lizardi PM, Shabanova VS, Levi A, Yaping T, Hu X, Feng Q. Cancer Prev Res (Phila). 2014 May; 2014 Feb 20. PMID: 24556390.

2010

Reversal of papilloma growth in rabbits therapeutically vaccinated against E6 with naked DNA and/or vesicular stomatitis virus vectors.Brandsma JL, Shlyankevich M, Su Y, Zelterman D, Rose JK, Buonocore L. Vaccine. 2010 Dec 6; 2009 Jul 15. PMID: 19615481.
Enhanced human papillomavirus type 8 oncogene expression levels are crucial for skin tumorigenesis in transgenic mice.Hufbauer M, Lazić D, Akgül B, Brandsma JL, Pfister H, Weissenborn SJ. Virology. 2010 Aug 1; 2010 May 7. PMID: 20451232.

2009

Distinct human papillomavirus type 16 methylomes in cervical cells at different stages of premalignancy.Brandsma JL, Sun Y, Lizardi PM, Tuck DP, Zelterman D, Haines GK 3rd, Martel M, Harigopal M, Schofield K, Neapolitano M. Virology. 2009 Jun 20; 2009 May 13. PMID: 19443004.

2007

Therapeutic vaccination of rabbits with a ubiquitin-fused papillomavirus E1, E2, E6 and E7 DNA vaccine.Brandsma JL, Shlyankevich M, Zelterman D, Su Y. Vaccine. 2007 Aug 14; 2007 Jun 26. PMID: 17630050.
Vesicular stomatitis virus-based therapeutic vaccination targeted to the E1, E2, E6, and E7 proteins of cottontail rabbit papillomavirus.Brandsma JL, Shylankevich M, Su Y, Roberts A, Rose JK, Zelterman D, Buonocore L. J Virol. 2007 Jun; 2007 Mar 28. PMID: 17392369.
Therapeutic efficacy of vesicular stomatitis virus-based E6 vaccination in rabbits.Brandsma JL, Shlyankevich M, Buonocore L, Roberts A, Becker SM, Rose JK. Vaccine. 2007 Jan 8; 2006 Aug 22. PMID: 16962690.
Particle-mediated gene delivery and human skin: ultrastructural observations on stratum corneum barrier structures.Menon GK, Brandsma JL, Schwartz PM. Skin Pharmacol Physiol. 2007; 2006 Oct 21. PMID: 17525512.

Yung-Chi Cheng

2006

Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and beta-L-2',3'-dideoxy-2',3'-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcitabine and beta-D-arabinofuranosylcytosine).Lam W, Park SY, Leung CH, Cheng YC. Mol Pharmacol. 2006 May; 2006 Feb 15. PMID: 16481390.
A novel manganese(III) acetate mediated reaction between 2-benzoyl-1,4-naphthoquinones and 1,3-dicarbonyl compounds.Lin CY, Cheng YC, Tsai AI, Chuang CP. Org Biomol Chem. 2006 Mar 21; 2006 Feb 8. PMID: 16525554.
Divergence of genes encoding B chains of beta-bungarotoxins.Cheng YC, Chen KC, Lin SK, Chang LS. Toxicon. 2006 Mar; 2006 Feb 2. PMID: 16457863.
Synthesis, antiviral, and antitumor activity of 2-substituted purine methylenecyclopropane analogues of nucleosides.Qin X, Chen X, Wang K, Polin L, Kern ER, Drach JC, Gullen E, Cheng YC, Zemlicka J. Bioorg Med Chem. 2006 Feb 15; 2005 Oct 18. PMID: 16242337.
Modification of Lys-6 and Lys-65 affects the structural stability of Taiwan cobra phospholipase A2.Chang LS, Cheng YC, Chen CP. Protein J. 2006 Feb. PMID: 16862455.
Coherence in the B800 ring of purple bacteria LH2.Cheng YC, Silbey RJ. Phys Rev Lett. 2006 Jan 20; 2006 Jan 17. PMID: 16486648.
3'-Carbon-substituted pyrimidine nucleosides having a 2',3'-dideoxy and 2',3'-didehydro-2',3'-dideoxy structure: synthesis and antiviral evaluation.Kumamoto H, Onuma S, Tanaka H, Dutschman GE, Cheng YC. Antivir Chem Chemother. 2006. PMID: 17066900.
Conversion of human umbilical cord mesenchymal stem cells in Wharton's jelly to dopaminergic neurons in vitro: potential therapeutic application for Parkinsonism.Fu YS, Cheng YC, Lin MY, Cheng H, Chu PM, Chou SC, Shih YH, Ko MH, Sung MS. Stem Cells. 2006 Jan; 2005 Aug 11. PMID: 16099997.

2005

New targets and inhibitors of HBV replication to combat drug resistance.Cheng YC, Ying CX, Leung CH, Li Y. J Clin Virol. 2005 Dec. PMID: 16461217.
Low prevalence of premature ovarian failure in women given reduced-intensity conditioning regimens for hematopoietic stem-cell transplantation.Cheng YC, Saliba RM, Rondón G, Giralt SA, Lu KH, Bodurka DC, Gershenson DM, Champlin RE, Ueno NT. Haematologica. 2005 Dec. PMID: 16330461.
Identification and functional characterization of Candida albicans CDC4.Shieh JC, White A, Cheng YC, Rosamond J. J Biomed Sci. 2005 Dec; 2005 Oct 14. PMID: 16228290.
Markovian approximation in the relaxation of open quantum systems.Cheng YC, Silbey RJ. J Phys Chem B. 2005 Nov 17. PMID: 16853776.
Biomarkers of exposure, effect, and susceptibility of arsenic-induced health hazards in Taiwan.Chen CJ, Hsu LI, Wang CH, Shih WL, Hsu YH, Tseng MP, Lin YC, Chou WL, Chen CY, Lee CY, Wang LH, Cheng YC, Chen CL, Chen SY, Wang YH, Hsueh YM, Chiou HY, Wu MM. Toxicol Appl Pharmacol. 2005 Aug 7. PMID: 15967209.
Anti-human immunodeficiency virus type 1 activity and resistance profile of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine in vitro.Nitanda T, Wang X, Kumamoto H, Haraguchi K, Tanaka H, Cheng YC, Baba M. Antimicrob Agents Chemother. 2005 Aug. PMID: 16048947.
Novel mechanism of inhibition of nuclear factor-kappa B DNA-binding activity by diterpenoids isolated from Isodon rubescens.Leung CH, Grill SP, Lam W, Han QB, Sun HD, Cheng YC. Mol Pharmacol. 2005 Aug; 2005 May 4. PMID: 15872117.
Clinical suppression of precocious puberty with cetrorelix after failed treatment with GnRH agonist in a girl with gonadotrophin-independent precocious puberty.Wu MH, Lin SJ, Wu LH, Cheng YC, Chou YY, Pan HA. Reprod Biomed Online. 2005 Jul. PMID: 16102281.
Emergency department response to SARS, Taiwan.Chen WK, Wu HD, Lin CC, Cheng YC. Emerg Infect Dis. 2005 Jul. PMID: 16022782.
Sox group E gene expression distinguishes different types and maturational stages of glial cells in developing chick and mouse.Kordes U, Cheng YC, Scotting PJ. Brain Res Dev Brain Res. 2005 Jun 30. PMID: 15878625.
Production of stilbenoids from the callus of Arachis hypogaea: a novel source of the anticancer compound piceatannol.Ku KL, Chang PS, Cheng YC, Lien CY. J Agric Food Chem. 2005 May 18. PMID: 15884811.
Poly(ADP-ribose) polymerase-1 could facilitate the religation of topoisomerase I-linked DNA inhibited by camptothecin.Park SY, Cheng YC. Cancer Res. 2005 May 1. PMID: 15867389.
Behavior of thymidylate kinase toward monophosphate metabolites and its role in the metabolism of 1-(2'-deoxy-2'-fluoro-beta-L-arabinofuranosyl)-5-methyluracil (Clevudine) and 2',3'-didehydro-2',3'-dideoxythymidine in cells.Hu R, Li L, Degrève B, Dutschman GE, Lam W, Cheng YC. Antimicrob Agents Chemother. 2005 May. PMID: 15855530.
Mechanism of anti-human immunodeficiency virus activity of beta-D-6-cyclopropylamino-2',3'-didehydro-2',3'-dideoxyguanosine.Ray AS, Hernandez-Santiago BI, Mathew JS, Murakami E, Bozeman C, Xie MY, Dutschman GE, Gullen E, Yang Z, Hurwitz S, Cheng YC, Chu CK, McClure H, Schinazi RF, Anderson KS. Antimicrob Agents Chemother. 2005 May. PMID: 15855524.
Active-passive gradient shielding for MRI acoustic noise reduction.Edelstein WA, Kidane TK, Taracila V, Baig TN, Eagan TP, Cheng YC, Brown RW, Mallick JA. Magn Reson Med. 2005 May. PMID: 15844137.
Chronic sclerosing sialadenitis of the parotid gland: diagnosis using color Doppler sonography and sonographically guided needle biopsy.Chou YH, Tiu CM, Li WY, Liu CY, Cheng YC, Chiou HJ, Chiou SY, Wang HK, Hung GS. J Ultrasound Med. 2005 Apr. PMID: 15784774.
Taiwan cobra chymotrypsin inhibitor: cloning, functional expression and gene organization.Cheng YC, Yan FJ, Chang LS. Biochim Biophys Acta. 2005 Mar 14; 2004 Dec 15. PMID: 15698956.
Phosphorylation of Cytidine, Deoxycytidine, and Their Analog Monophosphates by Human UMP/CMP Kinase Is Differentially Regulated by ATP and Magnesium.Hsu CH, Liou JY, Dutschman GE, Cheng YC. Mol Pharmacol. 2005 Mar; 2004 Nov 18. PMID: 15550676.
Effect of composition of poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) on growth of fibroblast and osteoblast.Wang YW, Yang F, Wu Q, Cheng YC, Yu PH, Chen J, Chen GQ. Biomaterials. 2005 Mar. PMID: 15350780.
Neuroradiological findings in atypical teratoid/rhabdoid tumor of the central nervous system.Cheng YC, Lirng JF, Chang FC, Guo WY, Teng MM, Chang CY, Wong TT, Ho DM. Acta Radiol. 2005 Feb. PMID: 15841745.
Prenatal diagnosis of fetal acrania using three-dimensional ultrasound.Liu IF, Chang CH, Yu CH, Cheng YC, Chang FM. Ultrasound Med Biol. 2005 Feb. PMID: 15708455.
Wnt1 regulates neurogenesis and mediates lateral inhibition of boundary cell specification in the zebrafish hindbrain.Amoyel M, Cheng YC, Jiang YJ, Wilkinson DG. Development. 2005 Feb; 2005 Jan 19. PMID: 15659486.
The impact of the SARS outbreak on an urban emergency department in Taiwan.Chen WK, Cheng YC, Chung YT, Lin CC. Med Care. 2005 Feb. PMID: 15655430.
Lys-64 of the A chain is involved in the enzymatic activity and neurotoxic effect of beta-bungarotoxin.Chang LS, Chu YP, Cheng YC, Liou JC, Yang CC. Toxicon. 2005 Feb. PMID: 15626367.
The structural events associated with the binding of divalent cations to beta-bungarotoxin.Chu YP, Cheng YC, Yang CC, Chang LS. Toxicon. 2005 Feb. PMID: 15626362.
Expression of deoxynucleotide carrier is not associated with the mitochondrial DNA depletion caused by anti-HIV dideoxynucleoside analogs and mitochondrial dNTP uptake.Lam W, Chen C, Ruan S, Leung CH, Cheng YC. Mol Pharmacol. 2005 Feb; 2004 Nov 11. PMID: 15539640.
Synthesis and antiviral activity of helioxanthin analogues.Yeo H, Li Y, Fu L, Zhu JL, Gullen EA, Dutschman GE, Lee Y, Chung R, Huang ES, Austin DJ, Cheng YC. J Med Chem. 2005 Jan 27. PMID: 15658867.
Nucleotides and pronucleotides of 2,2-bis(hydroxymethyl)methylenecyclopropane analogues of purine nucleosides: synthesis and antiviral activity.Yan Z, Kern ER, Gullen E, Cheng YC, Drach JC, Zemlicka J. J Med Chem. 2005 Jan 13. PMID: 15634003.
Phosphoralaninate pronucleotides of pyrimidine methylenecyclopropane analogues of nucleosides: synthesis and antiviral activity.Ambrose A, Zemlicka J, Kern ER, Drach JC, Gullen E, Cheng YC. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438046.
A new approach to the synthesis of 4'-carbon-substituted nucleosides: development of a highly active anti-HIV agent 2', 3'-didehydro-3'-deoxy-4'-ethynylthymidine.Haraguchi K, Takeda S, Sumino M, Tanaka H, Dutschman GE, Cheng YC, Nitanda T, Baba M. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247949.
4'-Ethynylstavudine (4'-Ed4T) has potent anti-HIV-1 activity with reduced toxicity and shows a unique activity profile against drug-resistant mutants.Tanaka H, Haraguchi K, Kumamoto H, Baba M, Cheng YC. Antivir Chem Chemother. 2005. PMID: 16130520.
Inhibition of hepatitis B virus gene expression and replication by helioxanthin and its derivative.Li Y, Fu L, Yeo H, Zhu JL, Chou CK, Kou YH, Yeh SF, Gullen E, Austin D, Cheng YC. Antivir Chem Chemother. 2005. PMID: 16004082.
Synthesis and biological evaluation of 2',3'-didehydro-2',3'-dideoxy-9-deazaguanosine, a monophosphate prodrug and two analogues, 2',3'-dideoxy-9-deazaguanosine and 2',3'-didehydro-2',3'-dideoxy-9-deazainosine.Liu MC, Luo MZ, Mozdziesz DE, Dutschman GE, Gullen EA, Cheng YC, Sartorelli AC. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 15822619.
Synthesis of (+/-)-4'-ethynyl and 4'-cyano carbocyclic analogues of stavudine (d4T).Kumamoto H, Haraguchi K, Tanaka H, Nitanda T, Baba M, Dutschman GE, Cheng YC, Kato K. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 15822615.
Purification and characterization of Taiwan cobra venom proteins with weak toxicity.Chang LS, Liou JC, Lin SR, Cheng YC. Toxicon. 2005 Jan. PMID: 15581679.

Susan Compton

2023

The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression.Wei J, Alfajaro MM, Cai WL, Graziano VR, Strine MS, Filler RB, Biering SB, Sarnik SA, Patel S, Menasche BL, Compton SR, Konermann S, Hsu PD, Orchard RC, Yan Q, Wilen CB. PLoS Pathog. 2023 Jul; 2023 Jul 6. PMID: 37410700.
The AALAS Journals: 2022 in Review.Toth LA, Compton SR, Tolwani RJ, Farrar JD, Brown AM. J Am Assoc Lab Anim Sci. 2023 Mar 1. PMID: 37061749.

2022

Modeling pandemic to endemic patterns of SARS-CoV-2 transmission using parameters estimated from animal model data.Mullin S, Wyk BV, Asher JL, Compton SR, Allore HG, Zeiss CJ. PNAS Nexus. 2022 Jul; 2022 Jul 1. PMID: 35799833.
The AALAS Journals: 2021 in Review.Toth LA, Compton SR, Tolwani RJ, Farrar JD. J Am Assoc Lab Anim Sci. 2022 Mar 1. PMID: 35321781.
Natural rodent model of viral transmission reveals biological features of virus population dynamics.Fay EJ, Balla KM, Roach SN, Shepherd FK, Putri DS, Wiggen TD, Goldstein SA, Pierson MJ, Ferris MT, Thefaine CE, Tucker A, Salnikov M, Cortez V, Compton SR, Kotenko SV, Hunter RC, Masopust D, Elde NC, Langlois RA. J Exp Med. 2022 Feb 7; 2021 Dec 27. PMID: 34958350.

2021

Modeling SARS-CoV-2 propagation using rat coronavirus-associated shedding and transmission.Zeiss CJ, Asher JL, Vander Wyk B, Allore HG, Compton SR. PLoS One. 2021; 2021 Nov 23. PMID: 34813610.
Overview of Coronaviruses in Veterinary Medicine.Compton SR. Comp Med. 2021 Oct 1; 2021 Aug 19. PMID: 34412731.
The AALAS Journals: 2020 in Review.Toth LA, Compton SR, Tolwani RJ, Dawson VK, Farrar JD. Comp Med. 2021 Apr 1. PMID: 33879279.
The AALAS Journals: 2020 in Review.Toth LA, Compton SR, Tolwani RJ, Dawson VK, Farrar JD. J Am Assoc Lab Anim Sci. 2021 Mar 1. PMID: 33762083.

2020

PCR and RT-PCR in the Diagnosis of Laboratory Animal Infections and in Health Monitoring.Compton SR. J Am Assoc Lab Anim Sci. 2020 Sep 1; 2020 Jun 24. PMID: 32580820.
Cutaneous and Pulmonary Mucormycosis in Rag1- and Il2rg-deficient Rats.Sarfaty AE, Compton SR, Smith PC, Zeiss CJ. Comp Med. 2020 Aug 1; 2020 Jul 31. PMID: 32736665.
The AALAS Journals: 2019 in Review.Toth LA, Compton SR, Tolwani RJ, Dawson VK, Farrar JD. Comp Med. 2020 Apr 1. PMID: 32220261.
Transverse myelitis following measles vaccination in a rhesus macaque (Macaca mulatta).Sarfaty AE, Fulbright RK, Compton SR, Asher JL, Zeiss CJ. J Med Primatol. 2020 Apr; 2019 Dec 2. PMID: 31789460.
The AALAS Journals: 2019 in Review.Toth LA, Compton SR, Tolwani RJ, Dawson VK, Farrar JD. J Am Assoc Lab Anim Sci. 2020 Mar 1. PMID: 32156333.

2019

Human PI3Kγ deficiency and its microbiota-dependent mouse model reveal immunodeficiency and tissue immunopathology.Takeda AJ, Maher TJ, Zhang Y, Lanahan SM, Bucklin ML, Compton SR, Tyler PM, Comrie WA, Matsuda M, Olivier KN, Pittaluga S, McElwee JJ, Long Priel DA, Kuhns DB, Williams RL, Mustillo PJ, Wymann MP, Koneti Rao V, Lucas CL. Nat Commun. 2019 Sep 25; 2019 Sep 25. PMID: 31554793.

2017

Lack of Effect of Murine Astrovirus Infection on Dextran Sulfate-induced Colitis in NLRP3-deficient Mice.Compton SR, Booth CJ, Macy JD. Comp Med. 2017 Oct 1. PMID: 28935001.
Murine Astrovirus Infection and Transmission in Neonatal CD1 Mice.Compton SR, Booth CJ, Macy JD. J Am Assoc Lab Anim Sci. 2017 Jul 1. PMID: 28724490.

2015

Torque-mixing magnetic resonance spectroscopy.Losby JE, Fani Sani F, Grandmont DT, Diao Z, Belov M, Burgess JA, Compton SR, Hiebert WK, Vick D, Mohammad K, Salimi E, Bridges GE, Thomson DJ, Freeman MR. Science. 2015 Nov 13. PMID: 26564851.
Effect of Cage-Wash Temperature on the Removal of Infectious Agents from Caging and the Detection of Infectious Agents on the Filters of Animal Bedding-Disposal Cabinets by PCR Analysis.Compton SR, Macy JD. J Am Assoc Lab Anim Sci. 2015 Nov. PMID: 26632784.

2014

Pathology in practice. HaPyV infection in a pet Syrian hamster.Beck AP, Compton SR, Zeiss CJ. J Am Vet Med Assoc. 2014 May 1. PMID: 24739112.
The AALAS journals: 2013 in review.Toth LA, Compton SR, Tolwani RJ, Bagaglio MH. Comp Med. 2014 Apr. PMID: 24674581.

2013

The AALAS journals: 2012 in review.Toth LA, Compton SR, Tolwani RJ. Comp Med. 2013 Aug. PMID: 24209964.
Effect of immunodeficiency on MPV shedding and transmission.Macy JD, Paturzo FX, Compton SR. J Am Assoc Lab Anim Sci. 2013 Jul. PMID: 23849445.
The AALAS journals: 2012 in review.Toth LA, Compton SR, Tolwani RJ. J Am Assoc Lab Anim Sci. 2013 Jul. PMID: 23849439.
Preimplantation factor reduces graft-versus-host disease by regulating immune response and lowering oxidative stress (murine model).Azar Y, Shainer R, Almogi-Hazan O, Bringer R, Compton SR, Paidas MJ, Barnea ER, Or R. Biol Blood Marrow Transplant. 2013 Apr; 2012 Dec 21. PMID: 23266739.

2012

Transmission of mouse parvovirus to neonatal mice.Compton SR, Paturzo FX, Macy JD. J Am Assoc Lab Anim Sci. 2012 Nov. PMID: 23294886.
Age-associated variability in susceptibility of Swiss Webster mice to MPV and other excluded murine pathogens.Grove KA, Smith PC, Booth CJ, Compton SR. J Am Assoc Lab Anim Sci. 2012 Nov. PMID: 23294885.
Transmission of mouse parvovirus by fomites.Compton SR, Paturzo FX, Smith PC, Macy JD. J Am Assoc Lab Anim Sci. 2012 Nov. PMID: 23294883.
Comparative Medicine and JAALAS Impact Factors--2011.Toth LA, Compton SR, Tolwani RJ, Bagaglio MH. J Am Assoc Lab Anim Sci. 2012. PMID: 23312080.

2011

Poliomyelitis in MuLV-infected ICR-SCID mice after injection of basement membrane matrix contaminated with lactate dehydrogenase-elevating virus.Carlson Scholz JA, Garg R, Compton SR, Allore HG, Zeiss CJ, Uchio EM. Comp Med. 2011 Oct. PMID: 22330347.
Detection and control of mouse parvovirus.Macy JD, Cameron GA, Smith PC, Ferguson TA, Compton SR. J Am Assoc Lab Anim Sci. 2011 Jul. PMID: 21838982.

2010

WAG-F8(m1Ycb) rats harboring a factor VIII gene mutation provide a new animal model for hemophilia A.Booth CJ, Brooks MB, Rockwell S, Murphy JW, Rinder HM, Zelterman D, Paidas MJ, Compton SR, Marks PW. J Thromb Haemost. 2010 Nov. PMID: 20626616.
Effect of murine norovirus infection on mouse parvovirus infection.Compton SR, Paturzo FX, Macy JD. J Am Assoc Lab Anim Sci. 2010 Jan. PMID: 20122310.

2009

Competing interests policy for AALAS journals.Toth LA, Compton SR, Tolwani R. Comp Med. 2009 Jun. PMID: 19619408.
A PCR-based strategy for detection of mouse parvovirus.Macy JD, Paturzo FX, Ball-Goodrich LJ, Compton SR. J Am Assoc Lab Anim Sci. 2009 May. PMID: 19476714.

2008

Prevention of murine norovirus infection in neonatal mice by fostering.Compton SR. J Am Assoc Lab Anim Sci. 2008 May. PMID: 18459709.

2007

Reliability of soiled bedding transfer for detection of mouse parvovirus and mouse hepatitis virus.Smith PC, Nucifora M, Reuter JD, Compton SR. Comp Med. 2007 Feb. PMID: 17348296.

2004

Pathogenesis of enterotropic mouse hepatitis virus in immunocompetent and immunodeficient mice.Compton SR, Ball-Goodrich LJ, Johnson LK, Johnson EA, Paturzo FX, Macy JD. Comp Med. 2004 Dec. PMID: 15679267.
Microbiological monitoring in individually ventilated cage systems.Compton SR, Homberger FR, MacArthur Clark J. Lab Anim (NY). 2004 Nov. PMID: 15514655.
Efficacy of three microbiological monitoring methods in a ventilated cage rack.Compton SR, Homberger FR, Paturzo FX, Clark JM. Comp Med. 2004 Aug. PMID: 15357318.
Persistent Seoul virus infection in Lewis rats.Compton SR, Jacoby RO, Paturzo FX, Smith AL. Arch Virol. 2004 Jul; 2004 Mar 17. PMID: 15221534.
Are we doing enough to protect mice from infectious agents?Smith PC, Compton SR. Comp Med. 2004 Jun. PMID: 15253269.
Transmission of enterotropic mouse hepatitis virus from immunocompetent and immunodeficient mice.Compton SR, Ball-Goodrich LJ, Paturzo FX, Macy JD. Comp Med. 2004 Feb. PMID: 15027615.

Peter Cresswell

2024

Cutting Edge: Phagosome-associated Autophagosomes Containing Antigens and Proteasomes Drive TAP-Independent Cross-Presentation.Sengupta D, Galicia-Pereyra R, Han P, Graham M, Liu X, Arshad N, Cresswell P. J Immunol. 2024 Apr 1. PMID: 38353614.
mosGILT controls innate immunity and germ cell development in Anopheles gambiae.Arora G, Tang X, Cui Y, Yang J, Chuang YM, Joshi J, Sajid A, Dong Y, Cresswell P, Dimopoulos G, Fikrig E. BMC Genomics. 2024 Jan 9; 2024 Jan 9. PMID: 38191283.

2023

A membrane-associated MHC-I inhibitory axis for cancer immune evasion.Chen X, Lu Q, Zhou H, Liu J, Nadorp B, Lasry A, Sun Z, Lai B, Rona G, Zhang J, Cammer M, Wang K, Al-Santli W, Ciantra Z, Guo Q, You J, Sengupta D, Boukhris A, Zhang H, Liu C, Cresswell P, Dahia PLM, Pagano M, Aifantis I, Wang J. Cell. 2023 Aug 31; 2023 Aug 8. PMID: 37557169.
Anopheles gambiae mosGILT regulates innate immune genes and zpg expression.Arora G, Tang X, Cui Y, Yang J, Chuang YM, Joshi J, Sajid A, Dong Y, Cresswell P, Dimopoulos G, Fikrig E. bioRxiv. 2023 Aug 2; 2023 Aug 2. PMID: 37577703.
CMPK2 restricts Zika virus replication by inhibiting viral translation.Pawlak JB, Hsu JC, Xia H, Han P, Suh HW, Grove TL, Morrison J, Shi PY, Cresswell P, Laurent-Rolle M. PLoS Pathog. 2023 Apr; 2023 Apr 19. PMID: 37075076.
SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to down-regulate MHC-I surface expression.Arshad N, Laurent-Rolle M, Ahmed WS, Hsu JC, Mitchell SM, Pawlak J, Sengupta D, Biswas KH, Cresswell P. Proc Natl Acad Sci U S A. 2023 Jan 3; 2022 Dec 27. PMID: 36574644.

2022

Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation.Jiang J, Taylor DK, Kim EJ, Boyd LF, Ahmad J, Mage MG, Truong HV, Woodward CH, Sgourakis NG, Cresswell P, Margulies DH, Natarajan K. Nat Commun. 2022 Sep 17; 2022 Sep 17. PMID: 36115831.
Protocol for assessing translational regulation in mammalian cell lines by OP-Puro labeling.Hsu JC, Pawlak JB, Laurent-Rolle M, Cresswell P. STAR Protoc. 2022 Sep 16; 2022 Aug 29. PMID: 36072758.
SARS-CoV-2 accessory proteins ORF7a and ORF3a use distinct mechanisms to downregulate MHC-I surface expression.Arshad N, Laurent-Rolle M, Ahmed WS, Hsu JC, Mitchell SM, Pawlak J, Sengupta D, Biswas KH, Cresswell P. bioRxiv. 2022 May 17; 2022 May 17. PMID: 35611331.
Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication.Hsu JC, Laurent-Rolle M, Pawlak JB, Xia H, Kunte A, Hee JS, Lim J, Harris LD, Wood JM, Evans GB, Shi PY, Grove TL, Almo SC, Cresswell P. Mol Cell. 2022 May 5; 2022 Mar 21. PMID: 35316659.

2021

Translational shutdown and evasion of the innate immune response by SARS-CoV-2 NSP14 protein.Hsu JC, Laurent-Rolle M, Pawlak JB, Wilen CB, Cresswell P. Proc Natl Acad Sci U S A. 2021 Jun 15. PMID: 34045361.
SARS-CoV-2 exacerbates proinflammatory responses in myeloid cells through C-type lectin receptors and Tweety family member 2.Lu Q, Liu J, Zhao S, Gomez Castro MF, Laurent-Rolle M, Dong J, Ran X, Damani-Yokota P, Tang H, Karakousi T, Son J, Kaczmarek ME, Zhang Z, Yeung ST, McCune BT, Chen RE, Tang F, Ren X, Chen X, Hsu JCC, Teplova M, Huang B, Deng H, Long Z, Mudianto T, Jin S, Lin P, Du J, Zang R, Su TT, Herrera A, Zhou M, Yan R, Cui J, Zhu J, Zhou Q, Wang T, Ma J, Koralov SB, Zhang Z, Aifantis I, Segal LN, Diamond MS, Khanna KM, Stapleford KA, Cresswell P, Liu Y, Ding S, Xie Q, Wang J. Immunity. 2021 Jun 8; 2021 May 9. PMID: 34048708.
Nilabh Shastri (1952-2021).Cresswell P. Immunity. 2021 Mar 9. PMID: 33691123.
Impact of Calreticulin and Its Mutants on Endoplasmic Reticulum Function in Health and Disease.Arshad N, Cresswell P. Prog Mol Subcell Biol. 2021. PMID: 34050866.

2020

HLA tapasin independence: broader peptide repertoire and HIV control.Bashirova AA, Viard M, Naranbhai V, Grifoni A, Garcia-Beltran W, Akdag M, Yuki Y, Gao X, O'hUigin C, Raghavan M, Wolinsky S, Bream JH, Duggal P, Martinson J, Michael NL, Kirk GD, Buchbinder SP, Haas D, Goedert JJ, Deeks SG, Fellay J, Walker B, Goulder P, Cresswell P, Elliott T, Sette A, Carlson J, Carrington M. Proc Natl Acad Sci U S A. 2020 Nov 10; 2020 Oct 23. PMID: 33097667.
Quantitating Endosomal Escape of a Library of Polymers for mRNA Delivery.Jiang Y, Lu Q, Wang Y, Xu E, Ho A, Singh P, Wang Y, Jiang Z, Yang F, Tietjen GT, Cresswell P, Saltzman WM. Nano Lett. 2020 Feb 12; 2020 Jan 31. PMID: 32003222.
Disruption of mosGILT in Anopheles gambiae impairs ovarian development and Plasmodium infection.Yang J, Schleicher TR, Dong Y, Park HB, Lan J, Cresswell P, Crawford J, Dimopoulos G, Fikrig E. J Exp Med. 2020 Jan 6. PMID: 31658986.

2019

Intrinsic expression of viperin regulates thermogenesis in adipose tissues.Eom J, Kim JJ, Yoon SG, Jeong H, Son S, Lee JB, Yoo J, Seo HJ, Cho Y, Kim KS, Choi KM, Kim IY, Lee HY, Nam KT, Cresswell P, Seong JK, Seo JY. Proc Natl Acad Sci U S A. 2019 Aug 27; 2019 Jul 24. PMID: 31341090.
Proteasomal degradation within endocytic organelles mediates antigen cross-presentation.Sengupta D, Graham M, Liu X, Cresswell P. EMBO J. 2019 Aug 15; 2019 Jul 4. PMID: 31271236.
A personal retrospective on the mechanisms of antigen processing.Cresswell P. Immunogenetics. 2019 Mar; 2019 Jan 29. PMID: 30694344.

2018

miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC.Jeon YJ, Kim T, Park D, Nuovo GJ, Rhee S, Joshi P, Lee BK, Jeong J, Suh SS, Grotzke JE, Kim SH, Song J, Sim H, Kim Y, Peng Y, Jeong Y, Garofalo M, Zanesi N, Kim J, Liang G, Nakano I, Cresswell P, Nana-Sinkam P, Cui R, Croce CM. Nat Commun. 2018 Nov 30; 2018 Nov 30. PMID: 30504895.
Cytosolic Processing Governs TAP-Independent Presentation of a Critical Melanoma Antigen.Vigneron N, Ferrari V, Van den Eynde BJ, Cresswell P, Leonhardt RM. J Immunol. 2018 Oct 1; 2018 Aug 22. PMID: 30135181.
The effect of additional mealtime insulin bolus using an insulin-to-protein ratio compared to usual carbohydrate counting on postprandial glucose in those with type 1 diabetes who usually follow a carbohydrate-restricted diet: A randomized cross-over trial.Krebs JD, Arahill J, Cresswell P, Weatherall M, Parry-Strong A. Diabetes Obes Metab. 2018 Oct; 2018 Jul 3. PMID: 29856114.
A novel probe to assess cytosolic entry of exogenous proteins.Lu Q, Grotzke JE, Cresswell P. Nat Commun. 2018 Aug 6; 2018 Aug 6. PMID: 30082832.
A mosquito salivary gland protein partially inhibits Plasmodium sporozoite cell traversal and transmission.Schleicher TR, Yang J, Freudzon M, Rembisz A, Craft S, Hamilton M, Graham M, Mlambo G, Tripathi AK, Li Y, Cresswell P, Sinnis P, Dimopoulos G, Fikrig E. Nat Commun. 2018 Jul 25; 2018 Jul 25. PMID: 30046053.
Tumor-associated calreticulin variants functionally compromise the peptide loading complex and impair its recruitment of MHC-I.Arshad N, Cresswell P. J Biol Chem. 2018 Jun 22; 2018 May 16. PMID: 29769311.
'And you'll suddenly realise 'I've not washed my hands': medical students', junior doctors' and medical educators' narratives of hygiene behaviours.Cresswell P, Monrouxe LV. BMJ Open. 2018 Mar 22; 2018 Mar 22. PMID: 29572392.

2017

Editing peptide presentation to T cells.Cresswell P. Science. 2017 Nov 24. PMID: 29170218.
Sec61 blockade by mycolactone inhibits antigen cross-presentation independently of endosome-to-cytosol export.Grotzke JE, Kozik P, Morel JD, Impens F, Pietrosemoli N, Cresswell P, Amigorena S, Demangel C. Proc Natl Acad Sci U S A. 2017 Jul 18; 2017 Jul 5. PMID: 28679634.
Structural studies of viperin, an antiviral radical SAM enzyme.Fenwick MK, Li Y, Cresswell P, Modis Y, Ealick SE. Proc Natl Acad Sci U S A. 2017 Jun 27; 2017 Jun 12. PMID: 28607080.
Editorial Overview: Antigen Processing and Presentation; many fingers in many pies.Cresswell P, Roche PA. Curr Opin Immunol. 2017 Jun; 2017 Jul 14. PMID: 28716443.
The ongoing saga of the mechanism(s) of MHC class I-restricted cross-presentation.Grotzke JE, Sengupta D, Lu Q, Cresswell P. Curr Opin Immunol. 2017 Jun; 2017 May 18. PMID: 28528219.
Viperin interaction with mitochondrial antiviral signaling protein (MAVS) limits viperin-mediated inhibition of the interferon response in macrophages.Hee JS, Cresswell P. PLoS One. 2017; 2017 Feb 16. PMID: 28207838.

2016

Access to diabetes drugs in New Zealand is inadequate.Krebs J, Coppell KJ, Cresswell P, Downie M, Drury P, Gregory A, Kenealy T, McNamara C, Miller SC, Smallman K. N Z Med J. 2016 Jun 10; 2016 Jun 10. PMID: 27355224.
Antigen Processing and Presentation Mechanisms in Myeloid Cells.Roche PA, Cresswell P. Microbiol Spectr. 2016 Jun. PMID: 27337472.
A randomised trial of the feasibility of a low carbohydrate diet vs standard carbohydrate counting in adults with type 1 diabetes taking body weight into account.Krebs JD, Parry Strong A, Cresswell P, Reynolds AN, Hanna A, Haeusler S. Asia Pac J Clin Nutr. 2016. PMID: 26965765.

2015

From 'pleasure to chemistry': the experience of carbohydrate counting with and without carbohydrate restriction for people with Type 1 diabetes.Cresswell P, Krebs J, Gilmour J, Hanna A, Parry-Strong A. J Prim Health Care. 2015 Dec 1; 2015 Dec 1. PMID: 26668834.
Are ERAD components involved in cross-presentation?Grotzke JE, Cresswell P. Mol Immunol. 2015 Dec; 2015 May 23. PMID: 26005101.
A congenital disorder of deglycosylation: Biochemical characterization of N-glycanase 1 deficiency in patient fibroblasts.He P, Grotzke JE, Ng BG, Gunel M, Jafar-Nejad H, Cresswell P, Enns GM, Freeze HH. Glycobiology. 2015 Aug; 2015 Apr 21. PMID: 25900930.
The transcription factor TFEB acts as a molecular switch that regulates exogenous antigen-presentation pathways.Samie M, Cresswell P. Nat Immunol. 2015 Jul; 2015 Jun 1. PMID: 26030023.

2014

Invariant chain-MHC class II complexes: always odd and never invariant.Cresswell P, Roche PA. Immunol Cell Biol. 2014 Jul; 2014 Apr 29. PMID: 24777311.
The informed consent process in randomised controlled trials: a nurse-led process.Cresswell P, Gilmour J. Nurs Prax N Z. 2014 Mar. PMID: 24839744.
Three tapasin docking sites in TAP cooperate to facilitate transporter stabilization and heterodimerization.Leonhardt RM, Abrahimi P, Mitchell SM, Cresswell P. J Immunol. 2014 Mar 1; 2014 Feb 5. PMID: 24501197.

2013

Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation.Salio M, Ghadbane H, Dushek O, Shepherd D, Cypen J, Gileadi U, Aichinger MC, Napolitani G, Qi X, van der Merwe PA, Wojno J, Veerapen N, Cox LR, Besra GS, Yuan W, Cresswell P, Cerundolo V. Proc Natl Acad Sci U S A. 2013 Dec 3; 2013 Nov 18. PMID: 24248359.
Intracellular regulation of cross-presentation during dendritic cell maturation.Wagner CS, Grotzke J, Cresswell P. PLoS One. 2013; 2013 Oct 3. PMID: 24098562.
Endoplasmic reticulum glycoprotein quality control regulates CD1d assembly and CD1d-mediated antigen presentation.Kunte A, Zhang W, Paduraru C, Veerapen N, Cox LR, Besra GS, Cresswell P. J Biol Chem. 2013 Jun 7; 2013 Apr 24. PMID: 23615906.
Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils.Leonhardt RM, Vigneron N, Hee JS, Graham M, Cresswell P. Mol Biol Cell. 2013 Apr; 2013 Feb 6. PMID: 23389629.
Role for lysosomal phospholipase A2 in iNKT cell-mediated CD1d recognition.Paduraru C, Bezbradica JS, Kunte A, Kelly R, Shayman JA, Veerapen N, Cox LR, Besra GS, Cresswell P. Proc Natl Acad Sci U S A. 2013 Mar 26; 2013 Mar 14. PMID: 23493550.
Deglycosylation-dependent fluorescent proteins provide unique tools for the study of ER-associated degradation.Grotzke JE, Lu Q, Cresswell P. Proc Natl Acad Sci U S A. 2013 Feb 26; 2013 Feb 11. PMID: 23401531.
Human CD1d knock-in mouse model demonstrates potent antitumor potential of human CD1d-restricted invariant natural killer T cells.Wen X, Rao P, Carreño LJ, Kim S, Lawrenczyk A, Porcelli SA, Cresswell P, Yuan W. Proc Natl Acad Sci U S A. 2013 Feb 19; 2013 Feb 4. PMID: 23382238.
Expanding roles for GILT in immunity.West LC, Cresswell P. Curr Opin Immunol. 2013 Feb; 2012 Dec 12. PMID: 23246037.
Viperin regulates cellular lipid metabolism during human cytomegalovirus infection.Seo JY, Cresswell P. PLoS Pathog. 2013; 2013 Aug 1. PMID: 23935494.
In vitro reconstitution of the MHC class I peptide-loading complex.Wearsch PA, Cresswell P. Methods Mol Biol. 2013. PMID: 23329479.
MHC class II-restricted presentation of the major house dust mite allergen Der p 1 Is GILT-dependent: implications for allergic asthma.West LC, Grotzke JE, Cresswell P. PLoS One. 2013; 2013 Jan 11. PMID: 23326313.
Pathways of antigen processing.Blum JS, Wearsch PA, Cresswell P. Annu Rev Immunol. 2013; 2013 Jan 3. PMID: 23298205.
Sibling rivalry: competition between MHC class II family members inhibits immunity.Denzin LK, Cresswell P. Nat Struct Mol Biol. 2013 Jan. PMID: 23288359.

2012

Dynamics of major histocompatibility complex class I association with the human peptide-loading complex.Panter MS, Jain A, Leonhardt RM, Ha T, Cresswell P. J Biol Chem. 2012 Sep 7; 2012 Jul 24. PMID: 22829594.
A switch in pathogenic mechanism in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in IFN-γ-inducible lysosomal thiol reductase-free mice.Bergman CM, Marta CB, Maric M, Pfeiffer SE, Cresswell P, Ruddle NH. J Immunol. 2012 Jun 15; 2012 May 14. PMID: 22586035.
Intracellular events regulating cross-presentation.Wagner CS, Grotzke JE, Cresswell P. Front Immunol. 2012; 2012 Jun 4. PMID: 22675326.
Inefficient exogenous loading of a tapasin-dependent peptide onto HLA-B*44:02 can be improved by acid treatment or fixation of target cells.Stroobant V, Demotte N, Luiten RM, Leonhardt RM, Cresswell P, Bonehill A, Michaux A, Ma W, Mulder A, Van den Eynde BJ, van der Bruggen P, Vigneron N. Eur J Immunol. 2012 Jun. PMID: 22678898.
GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals.Shenoy AR, Wellington DA, Kumar P, Kassa H, Booth CJ, Cresswell P, MacMicking JD. Science. 2012 Apr 27; 2012 Mar 29. PMID: 22461501.
TLR and nucleotide-binding oligomerization domain-like receptor signals differentially regulate exogenous antigen presentation.Wagner CS, Cresswell P. J Immunol. 2012 Jan 15; 2011 Dec 9. PMID: 22156493.
Interleukin-2 signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor.Metcalfe C, Cresswell P, Barclay AN. Open Biol. 2012 Jan. PMID: 22645657.

2011

Viperin: a multifunctional, interferon-inducible protein that regulates virus replication.Seo JY, Yaneva R, Cresswell P. Cell Host Microbe. 2011 Dec 15. PMID: 22177558.
Labile disulfide bonds are common at the leucocyte cell surface.Metcalfe C, Cresswell P, Ciaccia L, Thomas B, Barclay AN. Open Biol. 2011 Nov. PMID: 22645650.
The interferon-inducible gene viperin restricts West Nile virus pathogenesis.Szretter KJ, Brien JD, Thackray LB, Virgin HW, Cresswell P, Diamond MS. J Virol. 2011 Nov; 2011 Aug 31. PMID: 21880757.
Proteolysis of the class II-associated invariant chain generates a peptide binding site in intracellular HLA-DR molecules. Proc. Natl. Acad. Sci. USA. 1991. 88: 3150-3154.Roche PA, Cresswell P. J Immunol. 2011 Aug 1. PMID: 21772034.
Herpes simplex virus 1 glycoprotein B and US3 collaborate to inhibit CD1d antigen presentation and NKT cell function.Rao P, Pham HT, Kulkarni A, Yang Y, Liu X, Knipe DM, Cresswell P, Yuan W. J Virol. 2011 Aug; 2011 Jun 8. PMID: 21653669.
Disulfide reduction in the endocytic pathway: immunological functions of gamma-interferon-inducible lysosomal thiol reductase.Hastings KT, Cresswell P. Antioxid Redox Signal. 2011 Aug 1; 2011 Apr 20. PMID: 21506690.
Viperin mRNA is a novel target for the human RNase MRP/RNase P endoribonuclease.Mattijssen S, Hinson ER, Onnekink C, Hermanns P, Zabel B, Cresswell P, Pruijn GJ. Cell Mol Life Sci. 2011 Jul; 2010 Oct 30. PMID: 21053045.
Human cytomegalovirus directly induces the antiviral protein viperin to enhance infectivity.Seo JY, Yaneva R, Hinson ER, Cresswell P. Science. 2011 May 27; 2011 Apr 28. PMID: 21527675.
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentation.Paul P, van den Hoorn T, Jongsma ML, Bakker MJ, Hengeveld R, Janssen L, Cresswell P, Egan DA, van Ham M, Ten Brinke A, Ovaa H, Beijersbergen RL, Kuijl C, Neefjes J. Cell. 2011 Apr 15; 2011 Mar 31. PMID: 21458045.
Essential glycan-dependent interactions optimize MHC class I peptide loading.Wearsch PA, Peaper DR, Cresswell P. Proc Natl Acad Sci U S A. 2011 Mar 22; 2011 Mar 7. PMID: 21383180.
A role for UDP-glucose glycoprotein glucosyltransferase in expression and quality control of MHC class I molecules.Zhang W, Wearsch PA, Zhu Y, Leonhardt RM, Cresswell P. Proc Natl Acad Sci U S A. 2011 Mar 22; 2011 Mar 7. PMID: 21383159.
Proprotein convertases process Pmel17 during secretion.Leonhardt RM, Vigneron N, Rahner C, Cresswell P. J Biol Chem. 2011 Mar 18; 2011 Jan 19. PMID: 21247888.

2010

Calreticulin controls the rate of assembly of CD1d molecules in the endoplasmic reticulum.Zhu Y, Zhang W, Veerapen N, Besra G, Cresswell P. J Biol Chem. 2010 Dec 3; 2010 Sep 22. PMID: 20861015.
Identification of an alternate splice form of tapasin in human melanoma.Belicha-Villanueva A, Golding M, McEvoy S, Sarvaiya N, Cresswell P, Gollnick SO, Bangia N. Hum Immunol. 2010 Oct; 2010 Jun 20. PMID: 20600451.
GILT accelerates autoimmunity to the melanoma antigen tyrosinase-related protein 1.Rausch MP, Irvine KR, Antony PA, Restifo NP, Cresswell P, Hastings KT. J Immunol. 2010 Sep 1; 2010 Jul 28. PMID: 20668223.
Defective cross-presentation of viral antigens in GILT-free mice.Singh R, Cresswell P. Science. 2010 Jun 11. PMID: 20538950.
Endoplasmic reticulum export, subcellular distribution, and fibril formation by Pmel17 require an intact N-terminal domain junction.Leonhardt RM, Vigneron N, Rahner C, Van den Eynde BJ, Cresswell P. J Biol Chem. 2010 May 21; 2010 Mar 15. PMID: 20231267.
Viperin is highly induced in neutrophils and macrophages during acute and chronic lymphocytic choriomeningitis virus infection.Hinson ER, Joshi NS, Chen JH, Rahner C, Jung YW, Wang X, Kaech SM, Cresswell P. J Immunol. 2010 May 15; 2010 Apr 21. PMID: 20410488.
Antigen processing and presentation.Mellman I, Cresswell P. Curr Opin Immunol. 2010 Feb; 2010 Feb 19. PMID: 20172702.

2009

The antiviral protein, viperin, localizes to lipid droplets via its N-terminal amphipathic alpha-helix.Hinson ER, Cresswell P. Proc Natl Acad Sci U S A. 2009 Dec 1; 2009 Nov 17. PMID: 19920176.
Functional significance of tapasin membrane association and disulfide linkage to ERp57 in MHC class I presentation.Vigneron N, Peaper DR, Leonhardt RM, Cresswell P. Eur J Immunol. 2009 Sep. PMID: 19701894.
Kinetics and cellular site of glycolipid loading control the outcome of natural killer T cell activation.Im JS, Arora P, Bricard G, Molano A, Venkataswamy MM, Baine I, Jerud ES, Goldberg MF, Baena A, Yu KO, Ndonye RM, Howell AR, Yuan W, Cresswell P, Chang YT, Illarionov PA, Besra GS, Porcelli SA. Immunity. 2009 Jun 19. PMID: 19538930.
Natural lipid ligands associated with human CD1d targeted to different subcellular compartments.Yuan W, Kang SJ, Evans JE, Cresswell P. J Immunol. 2009 Apr 15. PMID: 19342656.
Viperin is required for optimal Th2 responses and T-cell receptor-mediated activation of NF-kappaB and AP-1.Qiu LQ, Cresswell P, Chin KC. Blood. 2009 Apr 9; 2008 Dec 1. PMID: 19047684.
Receptor-mediated phagocytosis elicits cross-presentation in nonprofessional antigen-presenting cells.Giodini A, Rahner C, Cresswell P. Proc Natl Acad Sci U S A. 2009 Mar 3; 2009 Feb 13. PMID: 19218463.
Role of individual domains and identification of internal gap in human guanylate binding protein-1.Abdullah N, Srinivasan B, Modiano N, Cresswell P, Sau AK. J Mol Biol. 2009 Feb 27; 2009 Jan 3. PMID: 19150356.
The N-terminal amphipathic alpha-helix of viperin mediates localization to the cytosolic face of the endoplasmic reticulum and inhibits protein secretion.Hinson ER, Cresswell P. J Biol Chem. 2009 Feb 13; 2008 Dec 12. PMID: 19074433.
Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer.Dong G, Wearsch PA, Peaper DR, Cresswell P, Reinisch KM. Immunity. 2009 Jan 16. PMID: 19119025.

2008

The quality control of MHC class I peptide loading.Wearsch PA, Cresswell P. Curr Opin Cell Biol. 2008 Dec; 2008 Oct 29. PMID: 18926908.
GILT is a critical host factor for Listeria monocytogenes infection.Singh R, Jamieson A, Cresswell P. Nature. 2008 Oct 30; 2008 Sep 24. PMID: 18815593.
C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients.Tykodi SS, Fujii N, Vigneron N, Lu SM, Mito JK, Miranda MX, Chou J, Voong LN, Thompson JA, Sandmaier BM, Cresswell P, Van den Eynde B, Riddell SR, Warren EH. Clin Cancer Res. 2008 Aug 15. PMID: 18698046.
The redox activity of ERp57 is not essential for its functions in MHC class I peptide loading.Peaper DR, Cresswell P. Proc Natl Acad Sci U S A. 2008 Jul 29; 2008 Jul 23. PMID: 18650385.
Target peptide sequence within infectious human immunodeficiency virus type 1 does not ensure envelope-specific T-helper cell reactivation: influences of cysteine protease and gamma interferon-induced thiol reductase activities.Sealy R, Chaka W, Surman S, Brown SA, Cresswell P, Hurwitz JL. Clin Vaccine Immunol. 2008 Apr; 2008 Jan 30. PMID: 18235043.
Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells.Giodini A, Cresswell P. EMBO J. 2008 Jan 9; 2007 Nov 29. PMID: 18046456.
Regulation of MHC class I assembly and peptide binding.Peaper DR, Cresswell P. Annu Rev Cell Dev Biol. 2008. PMID: 18729726.

2007

Aggregate formation by ERp57-deficient MHC class I peptide-loading complexes.Stepensky D, Bangia N, Cresswell P. Traffic. 2007 Nov; 2007 Sep 6. PMID: 17822402.
Severe tryptophan starvation blocks onset of conventional persistence and reduces reactivation of Chlamydia trachomatis.Leonhardt RM, Lee SJ, Kavathas PB, Cresswell P. Infect Immun. 2007 Nov; 2007 Aug 27. PMID: 17724071.